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BioXcell功能性抗体系列推荐-InVivoMAb anti-human CD3

2025-09-19     来源:本站     点击次数:65

产品信息:
 - 纯度: >95%
 - 内毒素:<2EU/mg
 - 货号:BE0001-2
 - Clone: OKT-3


应用类型:

in vitro T cell stimulation/activation
in vivo T cell depletion in humanized mice
ex vivo T cell inhibition for xenografts
Flow cytometry
 
参考文献:
1、"Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig" PLoS One 10(4): e0122198.​
2、"Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter" Eur J Immunol 45(4): 1103-1115.​
3、"The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells" Mol Cell 59(5): 840-849.​
4、"A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function" J Immunol 193(9): 4439-4447.​
5、"CD8(+) MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis" Eur J Immunol 44(10): 3119-3128.​
6、"Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles" J Immunol 193(2): 889-900.​
7、"OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues" Blood 123(24): e134-144.​
8、"VISTA is an immune checkpoint molecule for human T cells" Cancer Res 74(7): 1924-1932.
 
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