启维益成推出新品天然提取物大蒜素和萝卜硫素
2014-11-03 来源:本站 点击次数:6216大蒜素
大蒜素是大蒜中主要的生物活性化合物。它产生不同的生物效应，包括抗恶性细胞增殖，化学预防，抗氧化作用，抗高血脂和降压作用。研究已证明大蒜素可以抑制肿瘤细胞的生长。
产品描述
|
Cas 号 |
539-86-6 |
|
货号 |
A4440 |
|
产品名称 |
Allicin |
|
化学名称 |
Thio-2-propene-1-sulfinic acid S-allyl ester |
|
别名 |
Allylthiosulphinic acid allyl ester; Diallyl thiosulfinate |
|
分子量 |
162.27 |
|
熔点 |
<25 |
|
纯度 |
≥98% |
|
溶解性 |
Slightly soluble in water. Miscible with alcohol, ether, benzene. |
|
稳定性 |
Extremely heat sensitive. |
|
储存温度 |
-80oC |
|
运输温度 |
Dry Ice |
|
文献 |
Sela U, Ganor S, Hecht I., et al. Immunology. 11:391-399 (2004). Oommen S, Anto RJ, Srinivas G, et al. Eur J Pharmacol. 485:97-103 (2004). Sun L, Wang X. World J. Gastroenterol. 9:1930-1934 (2003). |
用LKT大蒜素所发表的文章：
抗菌
1. "Inhibition of streptolysin O by allicin - an active component of garlic."
M Arzanlou and S Bohlooli. J Med Microbiol, September 2010 vol. 59 no. 9 1044-1049. Epub June 10, 2010.
2. "Allicin-induced suppression of Mycobacterium tuberculosis 85B mRNA in human monocytes."
Hasan N, Siddiqui MU, Toossi Z, et al. Biochem Biophys Res Commun. 2007 Apr 6;355(2):471-6. Epub 2007 Feb 7.
抗癌
1. "Allicin Induces p53-Mediated Autophagy in Hep G2 Human Liver Cancer Cells."
Chu YL, Ho CT, Chung JG, et al. J Agric Food Chem. 2012 Aug 15.
2. "Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway."
Cha JH, Choi YJ, Cha SH, et al. Oncol Rep. 2012 Jul;28(1):41-8. doi: 10.3892/or.2012.1772. Epub 2012 Apr 23.
3. "Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2."
Bat-Chen W, Golan T, Peri I, et al. Nutr Cancer. 2010;62(7):947-57.
萝卜硫素
从西兰花里提取出来的手性天然产品。也是phase II 酶的诱导剂。在室温下，它是淡黄色粘稠液体。它的异硫氰酸盐基团与质子溶剂如水和乙醇反应形成相应的硫代氨基甲酸酯。它和半胱氨酸和谷胱甘肽上的巯基反应形成二硫代氨基甲酸酯（偶联物）。
产品描述
|
Cas 号 |
142825-10-3 |
|
货号 |
S8046 |
|
名称 |
R-Sulforaphane |
|
化学名称 |
1-Isothiocyanato-4-(methylsulfinyl)-butane |
|
别名 |
L-Sulforaphane |
|
分子量 |
177.29 |
|
纯度 |
≥98% |
|
溶解性 |
Soluble in DMSO, methanol, or water. |
|
储存温度 |
-20oC |
|
文献 |
Zhang, y., Talalay, P., Cho, C-G., Posner, G.H. Proc. Natl. Acad. Sci. USA. 89:2399-2403 (1992) |
用LKT萝卜硫素所发表的文章：
乳腺癌
1. "Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells."
Li Y, Zhang T, Korkaya H, et al. Clin Cancer Res May 1, 2010 16; 2580.
卵巢癌
2. "Antiproliferative activity of sulforaphane in Akt-overexpressing ovarian cancer cells."
Chaudhuri D, Orsulic S, Ashok BT. Mol Cancer Ther January 2007 6; 334.
前列腺癌
1. "Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells."
Bhamre S, Sahoo D, Tibshirani R, et al. Prostate. 2009; Feb. 1; 69(2): 181-190.
2. "Potent Induction of Phase 2 Enzymes in Human Prostate Cells by Sulforaphane."
Brooks JD, Paton VG, Vidanes G. Cancer Epidemiol Biomarkers Prev September 2001 10; 949
相关产品
大蒜素：http:///tools/search.asp?kw2=Allicin&tn=5
萝卜硫素：http:///tools/search.asp?kw2=R-Sulforaphane&tn=5
相关资讯
更多 >