NVP-BKM120 | PI3K 抑制剂
NVP-BKM120 - BKM 120
CAS 944396-07-0
C18H21F3N6O2 MW 410.39
Purity: >98%
Solubel in DMSO to 92 mM
Biological Activity:
Potent, selective, orally bioavailable class I PI3K inhibitor
References:
MT Burger et al. Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer. ACS Med. Chem. Lett. 2011, 2(10), 774–779. D Koul et al. Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells. Clin Cancer Res. 2012, 18(1), 184-195.
Chemical Name:
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NVP-BKM120 | PI3K inhibitor | Axon Medchem | Axon 1797 | BKM 120 |
Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.
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