RD 162 - RD162
C22H16F4N4O2S MW 476.46
Purity: >98%
Soluble in DMSO
Biological Activity:
An orally active and very potent antagonist of androgen receptor (AR); Second-generation of antiandrogen for the treatment of advanced prostate cancer; highly recommended tool in AR research.
References: online
C Tran et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 2009, 324 (5928), 787-790. [online]
C Harrison. Anticancer drugs: New approaches to anti-androgen activities. Nature Reviews Drug Discovery 2009, 8, 452-453. [online]
CJ Hoimes and WK Kelley. Redefining hormone resistance in prostate cancer. Ther Adv Med Oncol. 2010, 2(2), 107–123. [online]
Chemical Name: 4-[7-(4-Cyano-3-trifluoromethyl-phenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3.4]oct-5-yl]-2-fluoro-N-methyl-benzamide
Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.
单位名称: |
详细地址:
北京市海淀区西三旗建材城中路12号院8号楼3单元
|
qq:
2477120690
|
联系电话: |
Email: |