美国AAPPTec公司

Apex 396平行多肽合成仪


 

Apex 396平行合成仪，也称396多功能多肽合成仪。是目前世界上平行多肽合成和单通道多肽合成仪的市场领袖。Apex 396平行合成仪是作为生产药物研发库、丙氨酸扫描alanine scans、抗原表位定位和多肽平行试验库的理想仪器。合成规模从15毫克到2克。

高产量：

由于特氟龙反应器的独特设计，树脂停留在反应器底部，可以充分接触反应溶剂。基于这一点，树脂不会粘在反应器的边缘，因此Apex 396平行合成仪能够生产出更高产量的高纯度多肽。

高效率：

当维持一个惰性化境时，大气氮气辅助底部过滤能快速和彻底地排清反应器，结果就是快速清空。这个处理，结合快速输送，最小化多肽树脂分解应归于延长和酸的接触或者高效率彻底的清洗树脂以防止杂质转移。

高质量：

这些特性与优点使得Apex 396平行合成仪成为全自动环境温度平行多肽合成仪的最佳选择。



Apex 396平行合成仪是一个易于使用的自动化液体处理系统，能够胜任对液态、固相肽合成和有机合成反应。所有试剂、反应容器均在铝合金密封舱里，因此无需额外的通风橱设备。



 Apex 396平行合成仪支持多达96个化合物可以在四氟乙烯块内同时合成，同时也可以在40孔、16孔和8孔模式中选择合成。

Apex 396平行合成仪在96孔反应模式下，合成时间平均为30摩尔肽，每个肽20分钟。依据化学合成过程，氨基酸循环累加时间范围从45分钟到1.5个小时。


 Apex 396平行合成仪同轴喷雾探头传输溶剂精确度达到了0.5毫升。同轴探头有两个通道：用于溶剂和其他用于惰性气体（氮气或者氩气）。在溶剂送气过程中排出的溶剂替换为惰性气体；在溶剂传输过程中，气体保持贯彻整个合成。探头还负责液体的检测，通过鉴定测量溶剂的电容率。这可确保探头进入液面一下的溶剂，探头接触减少可减少宝贵样品之间的交叉污染。
 

灵活性：

*  Apex 396平行合成仪既可以生产单个肽，也可以同时生产少量肽或者最高同时
   生产96个肽。
*  双机器人臂精准的在任意两个点之间传输试剂。
*  密封罩内可以灵活地使用任何形状，尺寸或者放置容器
*  Apex 396平行合成仪可以灵活的支持任何化学类型，包括预激活氨基酸




混合模式：



* Apex 396平行合成仪具备柔和但是高效的涡旋混合可以完全混合树脂和试剂
* Apex 396平行合成仪涡旋混合提供了高度的一致性和持续性，保障了高质量高纯肽和蛋白质的生产。

Apex 396平行合成仪是当今市场上顶级的多肽合成仪。
 

Apex 396平行合成仪附件与部件列表

Reaction and Cleavage Assemblies 反应与切割部件 Catalog Number 货号 Part 部件 Description 描述 101476 96 Vessel Classic Reactor Assembly 96 two ml reactor assembly for preparing up to 96 different products simultaneously. 100018 96 Vessel Top Clamp Plate Top clamping plate for 96 Vessel Classic Reactor Assembly 99000101 96 Vessel Classic Cleavage Assembly Use with the 96 Vessel Reactor Assembly to cleave products from resin in 96 reactors and collect the products in 4 ml glass vials.  Glass vials included. 99001301 40 Vessel Classic Reactor Assembly 40 five ml reactor assembly for preparing up to 40 different products simultaneously. 102245 40 Vessel Top Clamp Plate Top clamping plate for 40 Vessel Classic Reactor Assembly 10241001 40 Vessel Classic Cleavage Assembly Use with the 40 Vessel Classic Reactor Assembly to cleave products from resin in 40 reactors and collect the products in 6 ml glass vials.  Glass vials included. 99001701 16 Vessel Classic Reactor Assembly 16 ten ml reactor assembly for preparing up to 16 different products simultaneously. 10238503 16 Vessel Top Clamp Plate Top clamping plate for 16 Vessel Classic Reactor Assembly 990008 16 Vessel Classic Cleavage Assembly Use with the 16 Vessel Classic Reactor Assembly to cleave products from resin in 16 reactors and collect the products in 15 ml glass beakers.  Glass beakers included. 99003501 8 Vessel Classic Reactor Assembly 8 twenty ml reactor assembly for preparing up to 8 different products simultaneously. 101249 8 Vessel Top Clamp Plate Top clamping plate for 8 Vessel Classic Reactor Assembly 990026 8 Vessel Classic Cleavage Assembly Use with the 8 Vessel Classic Reactor Assembly to cleave products from resin in 8 reactors and collect the products in 35 ml glass beakers.  Glass beakers included 10002401 Septa for Reactor Assembly Top Plate Use with all Classic Reactor Assemblies 10221301 Frits, Coarse, for 96 Vessel Classic Reactor Assembly Replacement frits for 96 vessel Classic Reactor assemblies 260062 Frits for 96 and 16 Vessel Classic Reactor Assemblies Replacement frits for 96 and 16 vessel Classic Reactor assemblies 10223401 Frits for 40 and 8 Vessel Classic Reactor Assemblies Replacement frits for 40 and 8 vessel Classic Reactor assemblies. 250946 Silicon Plugs for 96 and 16 Vessel Classic Reactor Assemblies Silicon plugs to plug unused vessels within an active zone in 96 and 16 vessel Classic reactor assemblies. 260166 Silicon Plugs for 40 and 8 Vessel Classic Reactor Assemblies Silicon plugs to plug unused vessels within an active zone in 40 and 8 vessel Classic reactor assemblies. 10002501 O-Ring, Reactor and Cleavage Assemblies O-Ring for Classic reactor and cleavage assemblies. 10002601 O-Ring, N2Pins O-ring that fits over the N2 pin in Classic reactor assemblies 950225 Resin Dispenser, 96 Vessel, 50 mg per vessel Simultaneously dispenses 50 mg of resin to each vessel of a 96 vessel Classic reactor or 96 vessel Ares reactor. 950418 Resin Dispenser, 40 Vessel, 35 mg per vessel Simultaneously dispenses 35 mg of resin to each vessel of a 40 vessel Classic reactor . 950251 Resin Dispenser, 96 Vessel, 25 mg per vessel Simultaneously dispenses 25 mg of resin to each vessel of a 96 vessel Classic reactor or 96 vessel Ares reactor.   Monomer Racks零件 Part Number Part Description 950165 4 x 9 Monomer Rack Assembly Rack contains 36 monomer bottles; each monomer bottle holds 35 mL. 10008801 35 mL Monomer Bottle (with cap) Fits 4 x 9 Monomer Rack 10009301 Cap with Hole for 35 mL Monomer Bottle Used with Septum 260237 10053001 Cap without Hole for 35 mL Monomer Bottle   260237 Septa For 35 mL Monomer Bottles 95001101 8 x 16 Monomer Rack Assembly Rack contains 124 monomer bottles; each monomer bottle holds 10 mL. 10083001 10 mL Monomer Bottle (with cap) Fits 8 x 16 Monomer Rack and 8 x 12 Monomer Rack 10139801 Cap with Hole for 10 mL Monomer Bottle Used with Septum 101396 101396 Septa For 10 mL Monomer Bottles 950169 8 x 12 Monomer Rack Assembly Rack contains 96 monomer bottles; each bottle holds 10 mL 950166 2 x 5 Monomer Rack Assembly Rack contains 10 monomer bottles; each monomer bottle holds 125 ml. 10139701 125 mL Monomer Bottle (with cap with hole) Fits 2 x 5 Monomer Rack 10139501 Septa For 125 mL Monomer Bottles 950043 18 - 18 Monomer Rack Assembly Rack contains eighteen 30 mL bottles and eighteen 10 mL bottles. 32000501 30 mL Monomer Bottle for 18 - 18 Monomer Rack 30 mL monomer bottle (29 x 82mm) for 18 - 18 Monomer Rack. 32000601 10 mL Monomer Bottle for 18 - 18 Monomer Rack 10 mL monomer bottle (24 x 72mm) for 18 - 18 Monomer Rack. 980110 5 x 6 Monomer Rack Assembly Rack holds 30 monomer bottles (950407); each bottle holds 125 mL 980111 5 x 5 Monomer Rack Assembly Rack holds 25 monomer bottles (950407); each bottle holds 125 mL. 980112 5 x 4 Monomer Rack Assembly Rack holds 20 monomer bottles (950407); each bottle holds 125 mL 980112 5 x 1 Monomer Rack Assembly Rack holds 5 monomer bottles (950407); each bottle holds 125 mL 950407 125 mL Monomer Bottles 125 mL Monomer bottles with septa.   Reagent Bottles反应瓶 Part Number 货号 Part 部件 Description 描述 10009101 300 mL Reagent Bottle Glass reagent bottle, with P/N 250881, fits on the tabletop of Apex 396 250881 Base for 300 mL Reagent Bottle Base for P/N 100091, fits on the tabletop of Apex 396 990299 800 mL Reagent Bottle (with stand) Larger reagent bottle for frequently used reagents and/or reagents used in larger quantities.  Fits on the tabletop of Apex 396. 320053 800 mL Oblong Reagent Bottle Larger reagent bottle for frequently used reagents and/or reagents used in larger quantities.  Fits on the tabletop of Apex 396. 260237 Septa Septa for 300 mL and 800 mL Reagent Bottles 260032 Lead Vinyl Ring For 300 mL and 800 mL Reagent Bottles   Parts部件 Part Number      货号 Description   描述 950370 Spray Probe 250299 4.1" Coaxial Probe for Multiprobe 250298 4.0" Coaxial Probe for Multiprobe 10074401 Diluter Valve 101376 Grommet, 10 mL Syringe Overrun Protection 260093 Syringe, 5 mL for Diluter 260251 Syringe, 10 mL for Diluter 10003902 Stainless Steel System Fluid Filter (Requires 10087201) 10087201 System Fluid Filter Adapter (Requires 10003902) 10050001 Isolation Block 100500A2 Isolation Block with Hole for Coaxial Probe 25005001 Ferrule for Coaxial Probe 106095 Fuse, 2X10 Amp Type T, 120V 106069 Fuse, 2X6.3 Amp Type T, 240V Apex 396平行合成仪是发表文献最多的多肽合成仪

关于美国AAPPTEC公司：



美国AAPPTEC公司，英文全称为Advanced Automated Peptide Protein Technologies公司,即美国先进自动多肽蛋白技术公司成立于2005年3月，公司的前身是ACT（Advanced ChemTech）公司的仪器部。AAPPTEC公司购买了前ACT公司仪器的全部资产，包括生产线，专利权以及在生产、促销和服务等方面的独家特权。AAPPTEC公司投入了充足的资源去提升和改进设备生产线，与此同时为药学界和生物领域提供了众多创新性新产品。 

AAPPTEC公司极其前身一直由Hossain Saneii博士来管理和运作整个公司，其总部设在美国肯塔吉州的路易斯维尔。近20年里，AAPPTEC公司在全自动多肽合成仪领域，针对不同的需求研发出数十种类型的仪器，加上长期实际应用验证的可靠性，这些仪器均可满足不同客户的不同需求，而且使用起来都相当便利，得到了全球用户的一致好评。AAPPTEC公司的多肽合成仪一定会满足您的需要，无论从仪器本身，到合成技术，到售后服务，我们在美国的工程师以及中国本土的高水平科学工作者也会一如既往地为您提供专业、周到的服务。

* 自然基因科技自2012年9月开始总代理美国AAPPTEC公司的产品。*

本产品提供1年全免费售后服务，包括产品介绍、送货、安装、调试、维修、技术培训服务等（与客户有特殊约定的按照约定执行）。

厂家产品链接：http://www.aapptec.com/custdocs/FocusXC%202_doc.pdf?osCsid=iilgldhkggg8t7eddr006ddq91

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