ATP结合蛋白家族6抗体--性能参数，报价/价格，图片

基本信息

产品名称：

ATP结合蛋白家族6抗体

英文名称：

ABCB6

国产/进口：

国产

产地/品牌：

bioss

型号：

bs-1224R

参考报价：

销售商：

北京博奥森生物技术有限公司

总点击数：

278

更新日期：

2017-05-03

产品类别：

抗体

性能参数

产品编号	bs-1224R
英文名称	ABCB6
中文名称	ATP结合蛋白家族6抗体
别名	ABC; ABC14; EST45597; ABC 14; ABC-14; ABCB 6; ABCB-6; PRP; UMAT; ABC transporter umat; MTABC3; Mt-ABC transporter 3; umat; Mitochondrial precursor; Mitochondrial ABC transporter 3; Mitochondrial abc protein 3; ATP-binding cassette, sub-family B, member 6, mitochondrial precursor; ATP binding cassette, sub family B (MDR/TAP), member 6; P glycoprotein related protein; Abcb6; ABCB6_HUMAN; ATP binding cassette sub family B member 6, mitochondrial precursor; ATP-binding cassette sub-family B member 6; Mitochondrial ABC transporter 3; mitochondrial; Mt ABC transporter 3; P-glycoprotein-related prote
规格价格	0.1ml/580元购买 0.2ml/960元购买
说明书	0.1ml 0.2ml
研究领域	肿瘤心血管信号转导新陈代谢线粒体
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig,
产品应用	ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	94kDa
细胞定位	细胞膜线粒体
性状	Lyophilized or Liquid
浓度	1mg/1ml
免疫原	KLH conjugated synthetic peptide derived from human ABCB6
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生产商	BIOSS
PubMed	PubMed
产品介绍	background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. Function: Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis Subunit: Homodimer. Subcellular Location: Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Tissue Specificity: Widely expressed. High expression is detected in the retinal epithelium. DISEASE: Microphthalmia, isolated, with coloboma, 7 (MCOPCB7) [MIM:614497]: A disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataract and other abnormalities like cataract may also be present. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain. Gene ID: 10058 Database links: Entrez Gene: 10058 Human Entrez Gene: 74104 Mouse Entrez Gene: 140669 Rat Omim: 605452 Human SwissProt: Q9NP58 Human SwissProt: Q9DC29 Mouse SwissProt: O70595 Rat SwissProt: Q9Z1S2 Rat Unigene: 107911 Human Unigene: 28663 Mouse Unigene: 54408 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ABCB6蛋白对于红细胞携带氧，肝细胞破坏毒素以及细胞从摄取营养物质后排放能量方面发挥重要的作用。

公司简介

北京博奥森生物技术有限公司成立于2001年，注册资本2000万元，是集免疫学科研试剂研发、生产、销售为一体的国家高新技术企业。在公司近1300平米的研发中心楼内，拥有SPF级实验动物房、GMP级单克隆抗体制备平台，同时购置了CSBio多肽合成仪、Akta全自动液相色谱系统、BD流式细胞仪、Leica冷冻切片机等多种生产、检测仪器。公司还拥有一批技术精湛、经验丰富的科研开发团队，在免疫和分子生物学等领域拥有多项自主知识产权。

自成立之初，公司始终秉持“自主研发、原始创新，为全球生命科学研究提供优质服务”的经营理念。提供全面的科研抗体、试剂，诊断抗体原料，以及CRO服务。公司现拥有近两万种抗体产品，涵盖人蛋白靶点13000多个。特色产品有特异磷酸化抗体及专利授权AF荧光标记抗体等。此外，公司还提供完善的单/多克隆抗体制备、标记、重组蛋白、多肽合成及各项免疫学检测技术服务等。公司恪守ISO9001:2008国际质量管理体系认证要求，致力于打造“Bioss”精品抗体品牌。 2010年博奥森（波士顿）在美国设立了面向全球抗体市场的商务拓展及国际市场营销总部，不断扩展全球销售体系，主打Bioss国际品牌，向全球科研工作者提供高质量的科研抗体产品。迄今为止，Bioss产品已遍布全球多个国家和地区，并已成为数家国际知名抗体公司的OEM合作伙伴。Bioss抗体产品已出现在数千篇高质量SCI文章中，获得了全世界众多生命科学领域科研人员的认可。

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