产品名：重组人白介素7（IL-7）

产品号：LT0118

产品信息：

白介素7是白介素2相关细胞因子家族的一员，通过受体的Yc亚单位，刺激T细胞的存活、增殖与平衡。白介素7可选择性扩增CD8⁺T细胞，而不是CD4⁺ FOXP3⁺ Treg细胞。在小鼠模型中，白介素7在注射疫苗或细胞治疗中可扩增抗原特异性T细胞，并在两项人体试验中得到验证。另外一项关于IL-7的临床数据显示其能够促进化疗或造血干细细胞移植后的T细胞恢复。

别名:

Lymphopoietin 1(LP-1), pre-B cell factor

描述:

IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.  Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.  Human and murine IL-7 are cross-species reactive.  Recombinant Human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.

氨基酸序列:

MDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH

来源:

E.coli

纯度&内毒素：

Greater than 95% by SDS-PAGE

gel and HPLC analyses.

Endotoxin Level<0.5EU/μg

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