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产品名称：重组人METAP1(甲硫氨酰氨肽酶1)(甲硫氨酸氨肽酶1)
英文名称：Recombinant Human Methionine Aminopeptidase 1
产品货号：JN1612
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Phe386表达纯化得来。

METAP1质量控制：＞95%(还原性SDS-PAGE)

METAP1制剂：液体

METAP1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于METAP1：
Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs.

根据您的关注的重组人METAP1(甲硫氨酰氨肽酶1)(甲硫氨酸氨肽酶1)，重组人甲硫氨酰氨肽酶1，重组METAP1，重组甲硫氨酸氨肽酶1，rhMETAP1，重组人METAP1，重组Methionine Aminopeptidase 1，重组人甲硫氨酸氨肽酶1，重组人Methionine Aminopeptidase 1，rMETAP1，重组甲硫氨酰氨肽酶1，Recombinant Human Methionine Aminopeptidase 1，您可能还对以下产品有需求：
 

货号	名称	规格
JN0323	重组人趋化因子CXCL8(IL-8)	10μg|50μg|500μg|1mg
JN0467	重组人TNF-α(C端His标签)	10μg|50μg|500μg|1mg
JN1899	重组人白血病抑制因子(LIF)	10μg|50μg|500μg|1mg
JN1930	重组人脂肪酸结合蛋白2(FABP2)	10μg|50μg|500μg|1mg
JN0591	重组人信号素5A(Semaphorin 5A)(Sema5A)	10μg|50μg|500μg|1mg
JN0736	重组人PACSIN1(神经元蛋白激酶C酪蛋白激酶底物1)	10μg|50μg|500μg|1mg

关注重组人METAP1(甲硫氨酰氨肽酶1)(甲硫氨酸氨肽酶1)，重组人甲硫氨酰氨肽酶1，重组METAP1，重组甲硫氨酸氨肽酶1，rhMETAP1，重组人METAP1，重组Methionine Aminopeptidase 1，重组人甲硫氨酸氨肽酶1，重组人Methionine Aminopeptidase 1，rMETAP1，重组甲硫氨酰氨肽酶1，Recombinant Human Methionine Aminopeptidase 1的同时，为您推荐更多您可能感兴趣的产品：



名称：重组人瓣状内切核酸酶1(FEN-1)
货号：JN1935
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Lys380表达纯化得来。

FEN-1质量控制：＞95%(还原性SDS-PAGE)

FEN-1制剂：液体

FEN-1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于FEN-1：
Flap Endonuclease 1 (FEN1) is a member of the XPG/RAD2 endonuclease family. During DNA replication, FEN1 cleaves the 5-overhanging flap structure and processes the 5 ends of Okazaki fragments for synthesis. FEN1 also exhibits RNase H activity by possessing 5-3 exonuclease activity on gapped double-stranded or nicked DNA, FEN1 is involved in the long patch base excision repair (LP-BER) pathway, it can cleave within the apurinic/apyrimidinic (AP) site-terminated flap. FEN1 can prevent flaps from equilibrating into structures that lead to duplications and deletions. FEN1 is also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

名称：重组人PDGFR-β(血小板衍生生长因子受体β)
货号：JN0539
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu33-Phe530在C端含有His标签。

PDGFR-β质量控制：＞95%(还原性SDS-PAGE)

PDGFR-β制剂：冻干品

PDGFR-β保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PDGFR-β复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PDGFR-β：
Platelet-Derived Growth Factor Receptor β (PDGFR-β) is a member of the protein kinase superfamily and CSF-1/PDGF receptor subfamily. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. The extracellular region of the PDGF receptor-β consists of five immunoglobulin-like domains while the intracellular part is a tyrosine kinase domain. In addition to being a potent mitogen for cells of mesenchymal origin, PDGF has also been shown to be a potent chemoattractant for mesenchymal cells, mononuclear cells, and neutrophils and has been reported to be important in the modification of cellular matrix constituents.