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产品名称：重组小鼠IFN-λ2/IL-28A
英文名称：Recombinant Murine Interferon-lambda 2/Interleukin-28A
产品货号：GS4697
产品规格：5μg

分子量：Approximately 19.7kDa,a single non-glycosylated polypeptide chain containing 174 amino acids.
储存条件：冷冻（-20℃）

概述

Murine IFN-lambda 2(IL-28A),IFN-lambda 3(IL-28B)are class II cytokine receptor ligands that are distantly related to members of the IL-10 family(11 - 13%amino acid sequence identity)and type I IFN family(15 - 19%a.a.sequence identity).These cytokines exert bioactivities that overlap those of type I IFNs,including antiviral activity and up-regulation of MHC class I antigen expression.The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta(IL-10 R beta)and a novel IL-28 receptor alpha(IL-28 R alpha,also known as IFN-lambda R1).Murine IL-28A shares 64%,65%,and 56%a.a.identity with human IL-28A,IL-28B,and IL-29,respectively.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 3ng/ml,corresponding to a specific activity of>3.3×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4,with 5%trehalose.
内毒素	Less than 0.1 EU/μg of rMuIFN-λ2/IL-28A as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	DPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKDAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENMTDS ALATILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFRLL TRDLKCVASG DQCV

根据您的关注的重组小鼠IFN-λ2/IL-28A，重组小鼠Murine Interferon-lambda 2/Interleukin-28A，重组Murine Interferon-lambda 2/Interleukin-28A，IFN-λ2/IL-28A, Murine，Recombinant Murine Interferon-lambda 2/Interleukin-28A，您可能还对以下产品有需求：


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关注重组小鼠IFN-λ2/IL-28A，重组小鼠Murine Interferon-lambda 2/Interleukin-28A，重组Murine Interferon-lambda 2/Interleukin-28A，IFN-λ2/IL-28A, Murine，Recombinant Murine Interferon-lambda 2/Interleukin-28A的同时，为您推荐更多您可能感兴趣的产品：



名称：重组小鼠趋化因子CCL24(Eotaxin-2)
货号：JN0320
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Val27-Val119表达纯化而来。

CCL24/Eotaxin-2质量控制：＞95%(还原性SDS-PAGE)。

CCL24/Eotaxin-2制剂：冻干品

CCL24/Eotaxin-2保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CCL24/Eotaxin-2复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CCL24/Eotaxin-2：
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, eosinophils and can bind to CCR3. LPS and IL4 also differentially regulate the expression of Ccl24 in monocytes and macrophages.