特别提示:包括重组人FGF19(成纤维细胞生长因子19)(带His标签)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人FGF19(成纤维细胞生长因子19)(带His标签)
英文名称:Recombinant Human Fibroblast growth factor 19
产品货号:JN0243
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Phe27-Lys216在N端含有His标签
FGF-19质量控制:>95%(还原性SDS-PAGE)。
FGF-19制剂:冻干品
FGF-19保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
FGF-19复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于FGF-19:
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.
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重组人FGF19(成纤维细胞生长因子19)(带His标签),重组FGF19,重组成纤维细胞生长因子19,rhFGF19,重组人成纤维细胞生长因子19,重组带His标签,重组人FGF19,重组Fibroblast growth factor 19,rFGF19,重组人Fibroblast growth factor 19,重组人带His标签,Recombinant Human Fibroblast growth factor 19,您可能还对以下产品有需求:
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重组人FGF19(成纤维细胞生长因子19)(带His标签),重组FGF19,重组成纤维细胞生长因子19,rhFGF19,重组人成纤维细胞生长因子19,重组带His标签,重组人FGF19,重组Fibroblast growth factor 19,rFGF19,重组人Fibroblast growth factor 19,重组人带His标签,Recombinant Human Fibroblast growth factor 19的同时,为您推荐更多您可能感兴趣的产品:
名称:重组人成纤维生长因子4
货号:JN0281
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ser54-Leu206表达纯化而来。
FGF-4质量控制:>95%(还原性SDS-PAGE)。
FGF-4制剂:冻干品
FGF-4保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
FGF-4复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于FGF-4:
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2c, 3c and 4, is spatially and temporally regulated during embryonic development. FGF-4 is proposed to play a physiologically relevant role in human embryonic stem cell selfrenewal. It promotes stem cell proliferation, but may also aid differentiation depending on context and concentration, and is often included in embryonic stem cell media in vitro. FGF-4 is mitogenic for fibroblasts and endothelial cells in vitro and has autocrine transforming potential. It is a potent angiogenesis promoter in vivo and has been investigated as therapy for coronary artery disease.