特别提示:包括重组人补体C8γ链(C8G)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人补体C8γ链(C8G)
英文名称:Recombinant Human Complement component C8 gamma chain
产品货号:JN1196
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Gln21-Arg202在N端含有His标签。
C8G质量控制:>95%(还原性SDS-PAGE)
C8G制剂:液体
C8G保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于C8G:
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
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