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产品名称:重组人巨噬细胞迁移抑制因子(MIF)
英文名称:Recombinant Human Macrophage migration inhibitory factor
产品货号:JN1188
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ala115表达纯化得来。
MIF质量控制:>95%(还原性SDS-PAGE)
MIF制剂:液体
MIF保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于MIF:
Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.
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重组人巨噬细胞迁移抑制因子(MIF),重组人MIF,重组Macrophage migration inhibitory factor,重组MIF,重组人Macrophage migration inhibitory factor,重组巨噬细胞迁移抑制因子,rhMIF,Recombinant Human Macrophage migration inhibitory factor,重组人巨噬细胞迁移抑制因子,rMIF的同时,为您推荐更多您可能感兴趣的产品:
名称:重组人GM-CSF(哺乳动物表达)(含His标签)
货号:JN0207
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Ala18-Glu144在C端含有His标签。
GM-CSF质量控制:>95%(还原性SDS-PAGE)。
GM-CSF制剂:冻干品
GM-CSF保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
GM-CSF复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于GM-CSF:
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.