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产品名称:重组人激肽释放酶(Kallikrein 7)(KLK7)
英文名称:Recombinant Human Kallikrein 7
产品货号:JN1712
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu23-His252在C端含有His标签。
Kallikrein 7质量控制:>95%(还原性SDS-PAGE)
Kallikrein 7制剂:液体
Kallikrein 7保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于Kallikrein 7:
Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.
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重组人激肽释放酶(Kallikrein 7)(KLK7),重组人Kallikrein 7,Recombinant Human Kallikrein 7,重组激肽释放酶,重组Kallikrein 7,重组人KLK7,rKLK7,重组人激肽释放酶,重组KLK7,rhKLK7,您可能还对以下产品有需求:
名称:重组人迁移率族蛋白B1(HMGB1)
货号:JN0533
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly2-Glu215在C端含有His标签。
HMGB1质量控制:>95%(还原性SDS-PAGE)
HMGB1制剂:液体
HMGB1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于HMGB1:
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.ItContains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
名称:重组人辅酶Q7(COQ7)
货号:JN0640
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser37-Leu217在C端含有His标签。
COQ7质量控制:>95%(还原性SDS-PAGE)
COQ7制剂:冻干品
COQ7保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
COQ7复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于COQ7:
Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) is a mitochondrion inner membrane and peripheral membrane protein which belongs to the COQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. COQ7 is involved in lifespan determination in ubiquinone-independent manner and also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator. Human COQ7 protein contains 179 amino acids, is mostly helical, and contains an alpha-helical membrane insertion. It has been shown that mutations in the gene are associated with increased life span. Defects of the gene slow down a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging.
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重组人激肽释放酶(Kallikrein 7)(KLK7),重组人Kallikrein 7,Recombinant Human Kallikrein 7,重组激肽释放酶,重组Kallikrein 7,重组人KLK7,rKLK7,重组人激肽释放酶,重组KLK7,rhKLK7的同时,为您推荐更多您可能感兴趣的产品: