特别提示：包括重组人IFN-ω在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人IFN-ω
英文名称：Recombinant Human Interferon-Omega
产品货号：GS4552
产品规格：20μg

分子量：Approximately 20.0kDa,containing 172 amino acid residues with two conserved disulfide bonds.
储存条件：冷冻（-20℃）

概述

Interferon-Omega(IFN-ω)coded by IFNW1 gene in human,is a number of the type I interferon family,which includes IFN-α,IFN-β,and IFN-ω.The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction,followed the antiviral or the antiproliferative actions.IFN-ω is derived from IFN-α/β and share 75%sequence with IFN-α.It has two intramolecular disulfide bonds which are crucial for activities.Mire-Sluis et al have described bioassays for IFN-α,IFN-β,and IFN-ω that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF.The bioassays can be used also with Epo and TF-1 cells,or Epo and Epo-transfected UT-7 cells.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01ng/ml,corresponding to a specific activity of>1.0×108 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuIFN-ω as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS

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