特别提示:包括重组人HDGF(肝癌衍生生长因子)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人HDGF(肝癌衍生生长因子)
英文名称:Recombinant Human Hepatoma-Derived Growth Factor
产品货号:JN0241
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Met1-Tyr100在C端含有His标签。
HDGF质量控制:>95%(还原性SDS-PAGE)。
HDGF制剂:冻干品
HDGF保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
HDGF复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于HDGF:
Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.
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重组人HDGF(肝癌衍生生长因子),重组肝癌衍生生长因子,重组人HDGF,重组HDGF,重组Hepatoma-Derived Growth Factor,重组人肝癌衍生生长因子,Recombinant Human Hepatoma-Derived Growth Factor,rhHDGF,rHDGF,重组人Hepatoma-Derived Growth Factor的同时,为您推荐更多您可能感兴趣的产品:
名称:重组小鼠EDA2R(TNFRSF27)(XEDAR)
货号:JN0493
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Met1-Thr138在C端含有His标签。
EDA2R/TNFRSF27/XEDAR 质量控制:>95%(还原性SDS-PAGE)
EDA2R/TNFRSF27/XEDAR 制剂:冻干品
EDA2R/TNFRSF27/XEDAR 保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
EDA2R/TNFRSF27/XEDAR 复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于EDA2R/TNFRSF27/XEDAR :
Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, EDA2R can associate with Fas and induce EDA‑A2 dependent apoptosis. Its transcription is directly induced by p53, and it mediated cell death is p53 dependent. it is down‑regulated in breast, colon, and lung cancers, particularly in cases with p53 mutations. It also plays a role in EDA‑A2 induced skeletal muscle degeneration and osteoblast differentiation. Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.