特别提示:包括重组小鼠OX40配体(TNFSF4)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组小鼠OX40配体(TNFSF4)
英文名称:Recombinant Mouse OX40 Ligand
产品货号:JN0494
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser51-Leu198在N端带有His标签。
OX40 Ligand/TNFSF4 质量控制:>95%(还原性SDS-PAGE)
OX40 Ligand/TNFSF4 制剂:冻干品
OX40 Ligand/TNFSF4 保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
OX40 Ligand/TNFSF4 复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于OX40 Ligand/TNFSF4 :
OX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. OX40L–OX40 co-stimulation leads to activation of TNF receptor associated factor (TRAF) 2, 3 and 5. This pathway has been shown to prolong the survival of effector CD4+Th cells as well as contributes to generation of memory T cells.
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重组小鼠OX40配体(TNFSF4),重组小鼠OX40配体,重组TNFSF4,rTNFSF4,重组OX40配体,重组小鼠TNFSF4,重组OX40 Ligand,Recombinant Mouse OX40 Ligand,rmTNFSF4,重组小鼠OX40 Ligand,您可能还对以下产品有需求:
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重组小鼠OX40配体(TNFSF4),重组小鼠OX40配体,重组TNFSF4,rTNFSF4,重组OX40配体,重组小鼠TNFSF4,重组OX40 Ligand,Recombinant Mouse OX40 Ligand,rmTNFSF4,重组小鼠OX40 Ligand的同时,为您推荐更多您可能感兴趣的产品:
名称:重组人TNFSF10(TRAIL)
货号:JN0437
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Arg115-Gly281表达纯化得来。
TNFSF10/TRAIL质量控制:>95%(还原性SDS-PAGE)
TNFSF10/TRAIL制剂:冻干品
TNFSF10/TRAIL保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TNFSF10/TRAIL复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TNFSF10/TRAIL:
Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.