特别提示：包括重组SARS-CoV-2 Papain-like Protease在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 Papain-like Protease
英文名称：Recombinant SARS-CoV-2 Papain-like Protease
产品货号：JN2065
产品规格：10μg|50μg

本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 Papain-like Protease（Glu1564-Lys187）。

Accession #:QHD43415.1

蛋白别称：Papain-like Protease;PLpro;PL-PRO;pp1a;Replicase polyprotein 1a

贮存液：20mM Tris-HCl,10mM Mercaptoethanol [BME],20% Glycerol,pH7.5，0.2μm过滤


质量控制：

分子量：35.8kDa
实测分子量：34kDa（还原条件下）
纯度：＞90%（还原SDS-PAGE）

保存条件：-20℃，可稳定保存6个月，应避免反复冻融。


背景资料：
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases,a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro).These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV.PLpro is a cysteine protease located within the non-structural protein 3 (NS3) section of the viral polypeptide.PLPro activity is required to process the viral polyprotein into functional,mature subunits;specifically,PLPro cleaves a site at the amino-terminus of the viral replicase region.In addition to its role in viral protein maturation,PLPro possesses a deubiquitinating and deISGylating activity.In vivo,this protease antagonizes innate immunity by inhibiting IRF3-induced production of type I interferons.

根据您的关注的重组SARS-CoV-2 Papain-like Protease(＞90%)，重组Replicase polyprotein 1a，重组新型冠状病毒PL-PRO，重组Papain-like Protease，重组SARS-CoV-2 Papain-like Protease，重组SARS-CoV-2木瓜蛋白酶样蛋白酶，rPLpro，rPL-PRO，重组新冠病毒PLpro，重组2019-nCoV Papain-like Protease，重组新型冠状病毒Papain-like Protease，Recombinant SARS-CoV-2 Papain-like Protease，重组pp1a，重组PL-PRO，rpp1a，重组PLpro，您可能还对以下产品有需求：


JN0250 重组小鼠VEGFD(血管内皮生长因子D)(带His标签) 10μg|50μg|500μg|1mg
JN0449 重组人补体C1q和TNF相关蛋白9(C1QTNF9) 10μg|50μg|500μg|1mg
JN0653 重组人信号素3C(Semaphorin 3C)(Sema3C) 10μg|50μg|500μg|1mg
JN0974 重组小鼠转谷氨酰胺酶2(TG2) 10μg|50μg|500μg|1mg
JN1014 重组人信号调节蛋白γ(SIRPG) 10μg|50μg|500μg|1mg
JN1021 重组人泛素结合酶E2-V2(UBE2V2) 10μg|50μg|500μg|1mg
JN1283 重组小鼠Syndecan-4(SDC4) 10μg|50μg|500μg|1mg

关注重组SARS-CoV-2 Papain-like Protease(＞90%)，重组Replicase polyprotein 1a，重组新型冠状病毒PL-PRO，重组Papain-like Protease，重组SARS-CoV-2 Papain-like Protease，重组SARS-CoV-2木瓜蛋白酶样蛋白酶，rPLpro，rPL-PRO，重组新冠病毒PLpro，重组2019-nCoV Papain-like Protease，重组新型冠状病毒Papain-like Protease，Recombinant SARS-CoV-2 Papain-like Protease，重组pp1a，重组PL-PRO，rpp1a，重组PLpro的同时，为您推荐更多您可能感兴趣的产品：



名称：重组人FGF2(碱性成纤维生长因子)
货号：JN0262
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Pro143-Ser288表达纯化而来。

FGF Basic质量控制：＞95%(还原性SDS-PAGE)。

FGF Basic制剂：冻干品

FGF Basic保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

FGF Basic复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于FGF Basic：
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells.