体外模拟消化
基本信息
产品名称：
体外模拟消化
英文名称：
国产/进口：
国产
产地/品牌：
晓东宜健
型号：
DIVHS(I)-IV
参考报价：
销售商：
总点击数：
275
更新日期：
2024-01-18
产品类别：
性能参数
体外模拟消化，是模拟人胃肠道消化过程，在体外条件下模拟体内消化吸收情况，用于预测或评估化合物的可消化性、生物利用率、释放动力学特性及结构变化等研究的体外模型。可选配小肠、大肠组件。体外消化系统可以或部分替代活体实验，具有降低成本和时间，提高实验重复性和准确性，人工可监控等优点。
体外消化系统可广泛应用于食品营养学，功能性活性物质代谢研究，药物释放动力研究，益生菌及益生元，食品毒理学研究等。
体外模拟消化原理
晓东宜健认为不同物种消化系统的规模特点不一样，同一种“小白鼠”不可能达到不同生物实验的要求。
准真实体外模拟消化系统：尽可能真实的模拟消化器官的形态/解剖结构/运动和生化环境。
“准真实”的体外消化模型不仅要模拟胃肠道内的物理运动和化学条件，还应提供真实的胃肠道形态。
DIVHS(I)-IV动态人胃（肠）体外消化系统应用
体外消化系统可广泛应用于食品营养学，功能性活性物质代谢研究，药物释放动力研究，益生菌及益生元，食品毒理学研究，大肠发酵，动物营养、动物消化及饲料研究等。
公司为客户量身定制，科学规划，提供专业的体外消化解决方案。可根据客户需求订制人胃模型，鼠胃模型，牛胃模型，猪胃模型，大肠发酵模型等。
应用领域：
脂肪代谢、蛋白质代谢、碳水化合物、多糖代谢、淀粉消化率、食物血糖指数、功能成分、微生物发酵、益生菌发酵、重金属影响、真菌毒素等、动物营养
DIVHS(I)-IV动态人胃（肠）体外消化系统技术参数（部分）
1、 触屏操作，PLC控制系统。
2、 人胃的压缩和蠕动频率为1-15cpm连续可调。
3、 十二指肠的蠕动频率为 1-40cpm连续可调。
4、 小肠蠕动推进速度0-3cm/s连续可调。
5、 大肠蠕动推进速度0-8cm/h连续可调。
DIVHS(I)-IV动态人胃（肠）体外消化系统发表文章（部分）
[1] Chen L, Jayemanne A, Chen X D. Venturing into in vitro physiological upper GI system focusing on the motility effect provided by a mechanised rat stomach model[J]. Food Digestion, 2013, 4(1):36-48.
以机械大鼠胃模型提供的动力效应为研究重点，研究体外生理上消化道系统
[2] Chen L, Wu X, Chen X D. Comparison between the digestive behaviors of a new in vitro rat soft stomach model with that of the in vivo experimentation on living rats - motility and morphological influences[J]. Journal of Food Engineering, 2013, 117(2):183-192.
新型体外大鼠胃软模型的消化行为与活体大鼠胃软模型的运动和形态影响的比较
[3] Wu P, Chen L, Wu X, et al. Digestive behaviours of large raw rice particles in vivo and in vitro rat stomach systems[J]. Journal of Food Engineering, 2014, 142:170-178.
大鼠胃系统在体内和体外的消化行为
[4] Chen L, Xu Y, Fan T, et al. Gastric emptying and morphology of a ‘near real' in vitro human stomach model (RD-IV-HSM)[J]. Journal of Food Engineering, 2016, 183:1-8.
胃排空与体外人胃模型(RD-IV-HSM)的形态学研究
[5] Wu P, Deng R, Wu X, et al. In vitro gastric digestion of cooked white and brown rice using a dynamic rat stomach model[J]. Food Chemistry, 2017, 237:1065.
采用动态大鼠胃模型对熟白米和糙米进行体外胃消化
[6] Wu P, Liao Z, Luo T, et al. Enhancement of digestibility of casein powder and raw rice particles in an improved dynamic rat stomach model through an additional rolling mechanism[J]. Journal of Food Science, 2017, 82(3).
在改进的动态大鼠胃模型中，通过额外的滚动机制提高酪蛋和生大米颗粒的消化率
[7] Bhattarai R R, Dhital S, Wu P, et al. Digestion of isolated legume cells in a stomach-duodenum model: three mechanisms limit starch and protein hydrolysis[J]. Food & Function, 2017, 8(7).
分离的豆科细胞在胃十二指肠模型中的消化研究：限制淀粉和蛋白质水解的三种机制
[8] Wu P, Bhattarai R R, Dhital S, et al. In vitro digestion of pectin- and mango-enriched diets using a dynamic rat stomach-duodenum model[J]. Journal of Food Engineering, 2017, 202:65-78.
用动态大鼠胃十二指肠模型体外消化富含果胶和芒果膳食
[9] Microwave pretreatment enhances the formation of cabbage sulforaphane and its bioaccessibility as shown by a novel dynamic soft rat stomach model[J]. Journal of Functional Foods, 2018, 43:186-195.
微波预处理增加了卷心菜萝卜硫素的形成及其生物可利用率
[10] Zhang X, Liao Z, Wu P, et al. Effects of the gastric juice injection pattern and contraction frequency on the digestibility of casein powder suspensions in an, in vitro, dynamic rat stomach made with a 3D printed model[J]. Food Research International, 2018, 106:495-502.
在3D打印模型的体外动态大鼠胃中，胃液注射模式和收缩频率对酪蛋悬浮液消化率的影响
[11] Zhao B, Sun S, Lin H, et al. Physicochemical properties and digestion of the lotus seed starch-green tea polyphenol complex under ultrasound-microwave synergistic interaction[J]. Ultrasonics Sonochemistry, 2018.
超声波-微波协同作用下莲子淀粉-绿茶多酚复合物的理化性质及消化情况
[12] Wang J, Wu P, Liu M H, et al. An advanced near real dynamic in vitro human stomach system to study gastric digestion and emptying of beef stew and cooked rice[J]. Food & Function, 2019.
一种先进的接近真实动态的体外人胃系统，用于研究炖牛肉和米饭的胃消化和排空
体外消化系统可广泛应用于食品营养学，功能性活性物质代谢研究，药物释放动力研究，益生菌及益生元，食品毒理学研究等。
体外模拟消化原理
晓东宜健认为不同物种消化系统的规模特点不一样，同一种“小白鼠”不可能达到不同生物实验的要求。
准真实体外模拟消化系统：尽可能真实的模拟消化器官的形态/解剖结构/运动和生化环境。
“准真实”的体外消化模型不仅要模拟胃肠道内的物理运动和化学条件，还应提供真实的胃肠道形态。
DIVHS(I)-IV动态人胃（肠）体外消化系统应用
体外消化系统可广泛应用于食品营养学，功能性活性物质代谢研究，药物释放动力研究，益生菌及益生元，食品毒理学研究，大肠发酵，动物营养、动物消化及饲料研究等。
公司为客户量身定制，科学规划，提供专业的体外消化解决方案。可根据客户需求订制人胃模型，鼠胃模型，牛胃模型，猪胃模型，大肠发酵模型等。
应用领域：
脂肪代谢、蛋白质代谢、碳水化合物、多糖代谢、淀粉消化率、食物血糖指数、功能成分、微生物发酵、益生菌发酵、重金属影响、真菌毒素等、动物营养
DIVHS(I)-IV动态人胃（肠）体外消化系统技术参数（部分）
1、 触屏操作，PLC控制系统。
2、 人胃的压缩和蠕动频率为1-15cpm连续可调。
3、 十二指肠的蠕动频率为 1-40cpm连续可调。
4、 小肠蠕动推进速度0-3cm/s连续可调。
5、 大肠蠕动推进速度0-8cm/h连续可调。
DIVHS(I)-IV动态人胃（肠）体外消化系统发表文章（部分）
[1] Chen L, Jayemanne A, Chen X D. Venturing into in vitro physiological upper GI system focusing on the motility effect provided by a mechanised rat stomach model[J]. Food Digestion, 2013, 4(1):36-48.
以机械大鼠胃模型提供的动力效应为研究重点，研究体外生理上消化道系统
[2] Chen L, Wu X, Chen X D. Comparison between the digestive behaviors of a new in vitro rat soft stomach model with that of the in vivo experimentation on living rats - motility and morphological influences[J]. Journal of Food Engineering, 2013, 117(2):183-192.
新型体外大鼠胃软模型的消化行为与活体大鼠胃软模型的运动和形态影响的比较
[3] Wu P, Chen L, Wu X, et al. Digestive behaviours of large raw rice particles in vivo and in vitro rat stomach systems[J]. Journal of Food Engineering, 2014, 142:170-178.
大鼠胃系统在体内和体外的消化行为
[4] Chen L, Xu Y, Fan T, et al. Gastric emptying and morphology of a ‘near real' in vitro human stomach model (RD-IV-HSM)[J]. Journal of Food Engineering, 2016, 183:1-8.
胃排空与体外人胃模型(RD-IV-HSM)的形态学研究
[5] Wu P, Deng R, Wu X, et al. In vitro gastric digestion of cooked white and brown rice using a dynamic rat stomach model[J]. Food Chemistry, 2017, 237:1065.
采用动态大鼠胃模型对熟白米和糙米进行体外胃消化
[6] Wu P, Liao Z, Luo T, et al. Enhancement of digestibility of casein powder and raw rice particles in an improved dynamic rat stomach model through an additional rolling mechanism[J]. Journal of Food Science, 2017, 82(3).
在改进的动态大鼠胃模型中，通过额外的滚动机制提高酪蛋和生大米颗粒的消化率
[7] Bhattarai R R, Dhital S, Wu P, et al. Digestion of isolated legume cells in a stomach-duodenum model: three mechanisms limit starch and protein hydrolysis[J]. Food & Function, 2017, 8(7).
分离的豆科细胞在胃十二指肠模型中的消化研究：限制淀粉和蛋白质水解的三种机制
[8] Wu P, Bhattarai R R, Dhital S, et al. In vitro digestion of pectin- and mango-enriched diets using a dynamic rat stomach-duodenum model[J]. Journal of Food Engineering, 2017, 202:65-78.
用动态大鼠胃十二指肠模型体外消化富含果胶和芒果膳食
[9] Microwave pretreatment enhances the formation of cabbage sulforaphane and its bioaccessibility as shown by a novel dynamic soft rat stomach model[J]. Journal of Functional Foods, 2018, 43:186-195.
微波预处理增加了卷心菜萝卜硫素的形成及其生物可利用率
[10] Zhang X, Liao Z, Wu P, et al. Effects of the gastric juice injection pattern and contraction frequency on the digestibility of casein powder suspensions in an, in vitro, dynamic rat stomach made with a 3D printed model[J]. Food Research International, 2018, 106:495-502.
在3D打印模型的体外动态大鼠胃中，胃液注射模式和收缩频率对酪蛋悬浮液消化率的影响
[11] Zhao B, Sun S, Lin H, et al. Physicochemical properties and digestion of the lotus seed starch-green tea polyphenol complex under ultrasound-microwave synergistic interaction[J]. Ultrasonics Sonochemistry, 2018.
超声波-微波协同作用下莲子淀粉-绿茶多酚复合物的理化性质及消化情况
[12] Wang J, Wu P, Liu M H, et al. An advanced near real dynamic in vitro human stomach system to study gastric digestion and emptying of beef stew and cooked rice[J]. Food & Function, 2019.
一种先进的接近真实动态的体外人胃系统，用于研究炖牛肉和米饭的胃消化和排空
公司简介
晓东宜健（苏州）仪器设备有限公司延承了自2004年提出的建设仿生体外消化吸收系统的概念，在澳大利亚Monash大学创建的“准真实”体外人胃系统和小鼠胃系统的基础上不断改良与完善，研发出一系列多样性的仿生消化系统。
许多食品、益生菌产品、口服医药等的研发过程里都需要有效的体外实验。通过建立和器官“高度相似”的设备，实现相应的生理机能，可以开展与医学相关的科学实验研究，协助理解消化道里的现象，从而达到体内实验难以实现的科研目标。
我们越来越意识到食品、药品在体内的“加工”过程与在体外的生产过程同样重要，甚至更为重要。体内消化吸收的过程及效率、消化系统内部的环境特征变化、肠道菌群的数量、种类、状态等，最终与我们是“三高”或是“忽高忽低”等都有直接的联系。食品营养健康也是个化学工程问题，例如：某食品进入体内后多长时间才能被消化分解，这个过程中又有哪种元素被吸收率较大或是无法被吸收，多种元素混合后将产生什么样的化学反应是否会导致消化不良......想要得出以上结论，需要解析人体内部的“化工过程”。同时，为了减少某些动物实验，晓东宜健结合化学工程、材料工程、机电工程、食品工程、医药工程、解剖学等缔造了一个接近真实的体外消化吸收检测系统。这样的产品可以助力体内现象的观察研究、帮助相关健康产品的开发、开展产品的测试等有意义的活动。
食品、口服药对我们的生活质量Life Quality (LQ) 有着巨大的影响。大量的前期实验是必要的。晓东宜健系列设备，在减少大量动物实验的同时，将使食品医药产业感受到“如虎添翼”。
当然，人类提高了自身生活质量的同时，也需要关注其他物种如何更科学地被保护或者更合理地被人类“利用”。饲料业的发展同样需要优秀、真实的体外消化吸收的监测系统。晓东宜健认为牛要有针对牛的高度仿生消化系统、猪要有猪的专门系统，鱼要有鱼的系统等等，以此类推。不同物种消化系统的规模、特点不一样，同一种“小白鼠”不可能达到不同生物实验的要求。
晓东宜健原创研发的“准器官”或“准真实”仿生体外消化系统的系列产品经过十几年的研究与磨砺，为不少科研机构、高校及企业提供了帮助。晓东宜健不会停止“开启未来”的脚步，将继续努力地、创造性地为人类生活质量工程（LQE）领域做最好的贡献。
Xiao Dong Pro-health (Suzhou) Instrumentation Co Ltd has been established based on an idea of biology-inspired chemical engineering created in 2004 at Auckland (New Zealand) and has now substantially extended the early primitive devices constructed for research at Monash University (Australia). These were considered as the Bio-mimic In Vitro Digestion-Absorption Systems. The human system and rat system, and a variety of related devices of different generations have been developed over these many years. Today, a range of modern devices are manufactured at the company.
In the development of functional foods including probiotics containing foods, and orally delivered medicines, etc., it is advantageous to have effective in vitro systems to perform pre-clinical experiments. Through designing and constructing realistic devices, realizing the desired physiological functions, one can progress on excellent scientific studies. The technology provides a Technical Platform for fundamental studies as well as product developments. These help understanding what is going on in the digestive tracks, realizing the objectives that are extremely difficult in vivo. The company laboratory is providing a range of testing services, which help achieve research goals and product development goals. Companies in food, pharmaceutical fields and universities are our usual clients.
How to create a relevant in vitro system that can reflect as close as possible the real situation? This has been a great challenge. The original idea here was that one could follow closely the anatomies of human and animals (geometrically, mechanically and biochemically) to make ‘organs’ of interest. Then, a range of mechanical, electrical and electronics, and computer programming aspects have to come in together to ensure the motility and functionality of the in vitro system(s) realistic. The designs can be age-dependent like child and adult. An effective in vitro system can help reducing the number of animals slaughtered for in vivo tests.
In addition to bio-mimic human systems, different animals due to their distinct differences in anatomies and functions in general should have their corresponding in vitro systems. These are relevant perhaps for developing animal feeds (stock foods or pet foods) etc. The company has established a general methodology to design and construct animal specific devices, chicken, pig, fish or even cow.
Through these years of developments and hard-working, rather realistic systems are available. The company is aiming at Improving Life Quality of People through its unique technologies and its future innovations. LQ essentially. We all know IQ and EQ are important qualities of an individual. LQ, on the other hand, is valid for everybody. The company is pushing forward with even greater ideas ahead.
Xiao Dong Pro-health (Suzhou) Instrumentation Co Ltd has been established based on an idea of biology-inspired chemical engineering created in 2004 at Auckland (New Zealand) and has now substantially extended the early primitive devices constructed for research at Monash University (Australia). These were considered as the Bio-mimic In Vitro Digestion-Absorption Systems. The human system and rat system, and a variety of related devices of different generations have been developed over these many years. Today, a range of modern devices are manufactured at the company.
In the development of functional foods including probiotics containing foods, and orally delivered medicines, etc., it is advantageous to have effective in vitro systems to perform pre-clinical experiments. Through designing and constructing realistic devices, realizing the desired physiological functions, one can progress on excellent scientific studies. The technology provides a Technical Platform for fundamental studies as well as product developments. These help understanding what is going on in the digestive tracks, realizing the objectives that are extremely difficult in vivo. The company laboratory is providing a range of testing services, which help achieve research goals and product development goals. Companies in food, pharmaceutical fields and universities are our usual clients.
How to create a relevant in vitro system that can reflect as close as possible the real situation? This has been a great challenge. The original idea here was that one could follow closely the anatomies of human and animals (geometrically, mechanically and biochemically) to make ‘organs’ of interest. Then, a range of mechanical, electrical and electronics, and computer programming aspects have to come in together to ensure the motility and functionality of the in vitro system(s) realistic. The designs can be age-dependent like child and adult. An effective in vitro system can help reducing the number of animals slaughtered for in vivo tests.
In addition to bio-mimic human systems, different animals due to their distinct differences in anatomies and functions in general should have their corresponding in vitro systems. These are relevant perhaps for developing animal feeds (stock foods or pet foods) etc. The company has established a general methodology to design and construct animal specific devices, chicken, pig, fish or even cow.
Through these years of developments and hard-working, rather realistic systems are available. The company is aiming at Improving Life Quality of People through its unique technologies and its future innovations. LQ essentially. We all know IQ and EQ are important qualities of an individual. LQ, on the other hand, is valid for everybody. The company is pushing forward with even greater ideas ahead.
售后服务
公司提供优质的售后服务：全套体外模拟消化系统，应用工程师可全程指导进行试验，直到可以独立上手。公司员工具有丰富的知识背景和专业技能，具有创新精神，有较强的责任感和团队合作能力，工作认真踏实的职业素养。
相关视频
暂无
资料下载
暂无
联系方式
| 单位名称： |
|
详细地址：
苏州市相城区黄埭镇安民路6号
|
|
qq：
3404284485
|
|
联系电话：
13564391812
|
| Email： |
