模拟口腔仿生系统
基本信息
产品名称：
模拟口腔仿生系统
英文名称：
国产/进口：
国产
产地/品牌：
晓东宜健
型号：
AOS-I
参考报价：
销售商：
总点击数：
379
更新日期：
2024-01-18
产品类别：
性能参数
模拟口腔仿生系统：口腔是享受好食品的“关口”。在口腔里食品与口水接触，经过咀嚼，混合，形成食团，然后被满足的吞咽。在口腔里的“加工”，对食物在胃里的消化过程有很大的影响。可以模拟婴幼儿，成年人，老年人的口腔咀嚼过程，“过程”各有特色。
模拟口腔仿生系统基于人体真实口腔参数设计，可以研究营养物质的释放以及咀嚼基质中活性，甚至有毒物质和食物污染物的释放，唾液浸渍的研究，口腔咀嚼消化的评价，针对目标人群设计的食品配方对食团及其特性的影响的研究，气味释放以及味道演变过程。关于口腔微生物/口腔菌群的研究也可以作为仿生口腔探索的一部分；直接将咀嚼过后形成的食团喂入动态人胃肠消化系统，进行一体化研究。
模拟口腔仿生系统的应用举例：
1. 模拟口腔仿生系统用于口腔咀嚼过程中气体释放及味道演变过程研究，究挥发性物质动态释放过程，可以直接连接GC,GC-MS,电子鼻，电子舌等感官分析设备；
2. 模拟口腔仿生系统用于假牙制作研究，例如：老年人口腔是首站，人类口腔的升级版研究，为老年人咀嚼创造更好的条件，用更少的力，达到更好的咀嚼状态，为假牙制造提供理论基础
3. 模拟口腔仿生系统为口腔类日化品（漱口水，牙膏等）研究提供得力助手。例如：口腔卫生，口腔中细菌去除效果研究，口腔微生物（口腔菌群）的研究，为口腔健康提供新力量。
4. 模拟口腔仿生系统用于其他研究。
模拟口腔仿生系统可设置参数等：可设置循环次数/咀嚼速率/上颚压力/唾液流速/温度等。实验参数按照 要求调节完毕后，设备全自动化操作。
模拟口腔仿生系统已经进行过多种食品的模拟咀嚼，以常见的食材大米为例，以体内和仿生口腔的结果展示：大米的粒径分布，剪切黏度和水分含量这些参数在体内和仿生机器上几乎相一致。
模拟口腔仿生系统基于人体真实口腔参数设计，可以研究营养物质的释放以及咀嚼基质中活性，甚至有毒物质和食物污染物的释放，唾液浸渍的研究，口腔咀嚼消化的评价，针对目标人群设计的食品配方对食团及其特性的影响的研究，气味释放以及味道演变过程。关于口腔微生物/口腔菌群的研究也可以作为仿生口腔探索的一部分；直接将咀嚼过后形成的食团喂入动态人胃肠消化系统，进行一体化研究。
模拟口腔仿生系统的应用举例：
1. 模拟口腔仿生系统用于口腔咀嚼过程中气体释放及味道演变过程研究，究挥发性物质动态释放过程，可以直接连接GC,GC-MS,电子鼻，电子舌等感官分析设备；
2. 模拟口腔仿生系统用于假牙制作研究，例如：老年人口腔是首站，人类口腔的升级版研究，为老年人咀嚼创造更好的条件，用更少的力，达到更好的咀嚼状态，为假牙制造提供理论基础
3. 模拟口腔仿生系统为口腔类日化品（漱口水，牙膏等）研究提供得力助手。例如：口腔卫生，口腔中细菌去除效果研究，口腔微生物（口腔菌群）的研究，为口腔健康提供新力量。
4. 模拟口腔仿生系统用于其他研究。
模拟口腔仿生系统可设置参数等：可设置循环次数/咀嚼速率/上颚压力/唾液流速/温度等。实验参数按照 要求调节完毕后，设备全自动化操作。
模拟口腔仿生系统已经进行过多种食品的模拟咀嚼，以常见的食材大米为例，以体内和仿生口腔的结果展示：大米的粒径分布，剪切黏度和水分含量这些参数在体内和仿生机器上几乎相一致。
公司简介
晓东宜健（苏州）仪器设备有限公司延承了自2004年提出的建设仿生体外消化吸收系统的概念，在澳大利亚Monash大学创建的“准真实”体外人胃系统和小鼠胃系统的基础上不断改良与完善，研发出一系列多样性的仿生消化系统。
许多食品、益生菌产品、口服医药等的研发过程里都需要有效的体外实验。通过建立和器官“高度相似”的设备，实现相应的生理机能，可以开展与医学相关的科学实验研究，协助理解消化道里的现象，从而达到体内实验难以实现的科研目标。
我们越来越意识到食品、药品在体内的“加工”过程与在体外的生产过程同样重要，甚至更为重要。体内消化吸收的过程及效率、消化系统内部的环境特征变化、肠道菌群的数量、种类、状态等，最终与我们是“三高”或是“忽高忽低”等都有直接的联系。食品营养健康也是个化学工程问题，例如：某食品进入体内后多长时间才能被消化分解，这个过程中又有哪种元素被吸收率较大或是无法被吸收，多种元素混合后将产生什么样的化学反应是否会导致消化不良......想要得出以上结论，需要解析人体内部的“化工过程”。同时，为了减少某些动物实验，晓东宜健结合化学工程、材料工程、机电工程、食品工程、医药工程、解剖学等缔造了一个接近真实的体外消化吸收检测系统。这样的产品可以助力体内现象的观察研究、帮助相关健康产品的开发、开展产品的测试等有意义的活动。
食品、口服药对我们的生活质量Life Quality (LQ) 有着巨大的影响。大量的前期实验是必要的。晓东宜健系列设备，在减少大量动物实验的同时，将使食品医药产业感受到“如虎添翼”。
当然，人类提高了自身生活质量的同时，也需要关注其他物种如何更科学地被保护或者更合理地被人类“利用”。饲料业的发展同样需要优秀、真实的体外消化吸收的监测系统。晓东宜健认为牛要有针对牛的高度仿生消化系统、猪要有猪的专门系统，鱼要有鱼的系统等等，以此类推。不同物种消化系统的规模、特点不一样，同一种“小白鼠”不可能达到不同生物实验的要求。
晓东宜健原创研发的“准器官”或“准真实”仿生体外消化系统的系列产品经过十几年的研究与磨砺，为不少科研机构、高校及企业提供了帮助。晓东宜健不会停止“开启未来”的脚步，将继续努力地、创造性地为人类生活质量工程（LQE）领域做最好的贡献。
Xiao Dong Pro-health (Suzhou) Instrumentation Co Ltd has been established based on an idea of biology-inspired chemical engineering created in 2004 at Auckland (New Zealand) and has now substantially extended the early primitive devices constructed for research at Monash University (Australia). These were considered as the Bio-mimic In Vitro Digestion-Absorption Systems. The human system and rat system, and a variety of related devices of different generations have been developed over these many years. Today, a range of modern devices are manufactured at the company.
In the development of functional foods including probiotics containing foods, and orally delivered medicines, etc., it is advantageous to have effective in vitro systems to perform pre-clinical experiments. Through designing and constructing realistic devices, realizing the desired physiological functions, one can progress on excellent scientific studies. The technology provides a Technical Platform for fundamental studies as well as product developments. These help understanding what is going on in the digestive tracks, realizing the objectives that are extremely difficult in vivo. The company laboratory is providing a range of testing services, which help achieve research goals and product development goals. Companies in food, pharmaceutical fields and universities are our usual clients.
How to create a relevant in vitro system that can reflect as close as possible the real situation? This has been a great challenge. The original idea here was that one could follow closely the anatomies of human and animals (geometrically, mechanically and biochemically) to make ‘organs’ of interest. Then, a range of mechanical, electrical and electronics, and computer programming aspects have to come in together to ensure the motility and functionality of the in vitro system(s) realistic. The designs can be age-dependent like child and adult. An effective in vitro system can help reducing the number of animals slaughtered for in vivo tests.
In addition to bio-mimic human systems, different animals due to their distinct differences in anatomies and functions in general should have their corresponding in vitro systems. These are relevant perhaps for developing animal feeds (stock foods or pet foods) etc. The company has established a general methodology to design and construct animal specific devices, chicken, pig, fish or even cow.
Through these years of developments and hard-working, rather realistic systems are available. The company is aiming at Improving Life Quality of People through its unique technologies and its future innovations. LQ essentially. We all know IQ and EQ are important qualities of an individual. LQ, on the other hand, is valid for everybody. The company is pushing forward with even greater ideas ahead.
Xiao Dong Pro-health (Suzhou) Instrumentation Co Ltd has been established based on an idea of biology-inspired chemical engineering created in 2004 at Auckland (New Zealand) and has now substantially extended the early primitive devices constructed for research at Monash University (Australia). These were considered as the Bio-mimic In Vitro Digestion-Absorption Systems. The human system and rat system, and a variety of related devices of different generations have been developed over these many years. Today, a range of modern devices are manufactured at the company.
In the development of functional foods including probiotics containing foods, and orally delivered medicines, etc., it is advantageous to have effective in vitro systems to perform pre-clinical experiments. Through designing and constructing realistic devices, realizing the desired physiological functions, one can progress on excellent scientific studies. The technology provides a Technical Platform for fundamental studies as well as product developments. These help understanding what is going on in the digestive tracks, realizing the objectives that are extremely difficult in vivo. The company laboratory is providing a range of testing services, which help achieve research goals and product development goals. Companies in food, pharmaceutical fields and universities are our usual clients.
How to create a relevant in vitro system that can reflect as close as possible the real situation? This has been a great challenge. The original idea here was that one could follow closely the anatomies of human and animals (geometrically, mechanically and biochemically) to make ‘organs’ of interest. Then, a range of mechanical, electrical and electronics, and computer programming aspects have to come in together to ensure the motility and functionality of the in vitro system(s) realistic. The designs can be age-dependent like child and adult. An effective in vitro system can help reducing the number of animals slaughtered for in vivo tests.
In addition to bio-mimic human systems, different animals due to their distinct differences in anatomies and functions in general should have their corresponding in vitro systems. These are relevant perhaps for developing animal feeds (stock foods or pet foods) etc. The company has established a general methodology to design and construct animal specific devices, chicken, pig, fish or even cow.
Through these years of developments and hard-working, rather realistic systems are available. The company is aiming at Improving Life Quality of People through its unique technologies and its future innovations. LQ essentially. We all know IQ and EQ are important qualities of an individual. LQ, on the other hand, is valid for everybody. The company is pushing forward with even greater ideas ahead.
售后服务
公司提供优质的售后服务：全套体外模拟消化系统，应用工程师可全程指导进行试验，直到可以独立上手。公司员工具有丰富的知识背景和专业技能，具有创新精神，有较强的责任感和团队合作能力，工作认真踏实的职业素养。
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