【Fibronectin】人纤连蛋白

【产品描述】：Plasma fibronectin level is elevated in severe coronary artery disease. Increased plasma fibronectin levels are related with venous thromboembolism (VTE) particularly in males, and extend the probable association between biomarkers and risk factors for arterial atherothrombosis and VTE. Fibronectin plays a role in several cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin consists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the etracellular matrix and 2) as a soluble disulphide linked dimer found in the plasma. The plasma form is produced by hepatocytes, and the ECM form is synthesized by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells. Fibronectin alos takes part as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. Fibronectin organizes cellular interaction with the ECM by binding to different components of the extracellular matrix and to membrane-bound Fibronectin receptors on cell surfaces. Molecular Weight 450kDa.

【蛋白来源】：人血浆中提取纯化

【溶解建议】：Sterile Filtered White lyophilized (freeze-dried) powder. The Fibronectin was lyophilized from a concentrated 1mg/ml solution containing 0.05M Tris HCl pH-7.5 and 0.1M NaCl. Purified fibronectin has a tendency to form insoluble aggregates upon reconstitution. We suggest to reconstittue the 1mg Fibronectin with a chaotropic agent such as urea at room temperature at a concentration of 0.2mg/ml using sterile water. Let stand 1-2 hours.

【保存建议】：Lyophilized Fibronectin although stable at room temperature for 1 week, should be stored desiccated below -18℃. Upon reconstitution Fibronectin should be stored at 4℃ between 2-7 days and for future use below -18℃. Please prevent freeze-thaw cycles.

以色列ProSpec公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流的细胞因子、生长因子、趋化因子等科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。作为ProSpec中国区域总代理，艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。

更详细产品说明及价格请点击【Fibronectin】人纤连蛋白查询或致电400-6800-868与ProSpec中国区域授权总代理艾美捷科技有限公司垂询。