离子通道稳转细胞系
基本信息
产品名称：
离子通道稳转细胞系
英文名称：
国产/进口：
进口
产地/品牌：
瑞士/神思药得
型号：
Nav1.8，hERG， Nav1.5
参考报价：
销售商：
总点击数：
376
更新日期：
2025-05-27
产品类别：
性能参数
神思药得科技提供优化过的稳定表达离子通道细胞系，通道序列清晰，完成全套的表达验证、功能测试、微生物检测和健康认证，提供完整的细胞授权文件以满足GLP实验和申报的需求。
细胞系包括Nav1.8, hERG, Nav1.5, Cav1.2, GABAa等。优化后的细胞株质量可靠，电流清晰，可保证膜片钳分析能获得稳定的实验数据。可应用在癫痫、镇痛等多个领域离子通道靶点药物高通量筛选和早期药物研发，亦可满足临床前心脏安全性评价CiPA需求。
- 全套验证文件与授权
- 经过专门优化挑选
- 易形成紧密高阻抗封接
- 优化的成功率
- 稳定的电流反应
- 优化的实验溶液配方和标准化细胞培养方案
- 实验技术支持
- 用户定制与分析
- 基于稳转细胞株的药物筛选和检测服务
更多其他离子通道稳转细胞系和检测服务，欢迎留言详询。
现有离子通道细胞系（进口）列表：
电压门控类
Potassium channels
| Target | Gene | Disorder | Cell Type | |
| KV1.1 | KCNA1 | Seizure disorders | CHO | |
| KV1.2 | KCNA2 | Seizure disorders | CHO | |
| KV1.3 | KCNA3 | Immune system related | CHO | |
| KV1.4 | KCNA4 | - | CHO | |
| KV1.5 | KCNA5 | Heart function | CHO | |
| KV1.6 | KCNA6 | - | CHO | |
| KV1.7 | KCNA7 | - | CHO | |
| KV2.1 | KCNB1 | - | CHO | |
| KV2.1 | KCNB1 | HEK 293 | ||
| KV2.2 | KCNB2 | - | CHO | |
| KV2.2 | KCNB2 | - | HEK 293 | |
| KV3.1a (short) | KCNC1 | - | CHO | |
| KV3.1b (long) | KCNC1 | - | CHO | |
| KV3.2 | KCNC2 | - | CHO | |
| KV3.3 | KCNC3 | - | CHO | |
| KV3.4 | KCNC4 | - | CHO | |
| KV4.2 | KCND2 | - | CHO | |
| KV4.3 | KCND3 | - | CHO | |
| KV4.3 | KCND3 | - | HEK 293 | |
| KV4.3 KChip | KCND3 | - | CHO | |
| KV7.1 (KVLQT1) | KCNQ1 | - | HEK 293 | |
| KV7.1 (KVLQT1) | KCNQ1 | LQT Syndrome 1/5 | HEK 293 | |
| KV7.1 (KVLQT1) | KCNQ1 | LQT Syndrome 1/5 | CHO | |
| KVLQT1/minK | KCNQ1/KCNE1 | LQT Syndrome 1/5 | HEK 293 | |
| KVLQT1/minK | KCNQ1/KCNE1 | LQT Syndrome 1/5 | CHO | |
| KV7.2 | KCNQ2 | Epilepsy | CHO | |
| KV7.3 | KCNQ3 | Epilepsy | CHO | |
| KV7.2/3 | KCNQ2/3 | Epilepsy | CHO | |
| KV7.2/3 (rat) | KCNQ2/3 | Epilepsy | CHO | |
| KV7.3/5 | KCNQ3/5 | - | CHO | |
| KV10.1 | KCNH1 | - | CHO | |
| K2P18.1 | KCNK18 | - | HEK 293 | |
| SK4 KCa3.1 | KCNN4 | - | CHO | |
| hERG | KCNH2 | LQT Syndrome 2 | HEK 293 | |
| hERG | KCNH2 | LQT Syndrome 2 | HEK 293 | |
| hERG | KCNH2 | LQT Syndrome 2 | CHO | |
| hERG | KCNH2 | LQT Syndrome 2 | CHO | |
| hERG Duo | KCNH2 | LQT Syndrome 2 | CHO | |
| Kir1.1 | KCNJ1 | - | CHO | |
| Kir2.1 | KCNJ2 | LQT Syndrome | CHO | |
| Kir2.2 | KCNJ12 | - | CHO | |
| Kir2.3 | KCNJ4 | - | HEK 293 | |
| Kir2.3 | KCNJ4 | - | CHO | |
| BK α1 | KCNMA1 | - | CHO | |
| BK α1 | KCNMA1 | - | CHO | |
| BK α1β2 | KCNMA1 / KCNMB2 | - | CHO | |
| BK α1β4 | KCNMA1 / KCNMB4 | - | CHO | |
| KCa2.2 (SK2) | KCNN1 | - | CHO | |
|
KCa2.1 / KCa2.2 (SK1/SK2)
|
KCNN2 / KCNN1 | - | CHO | |
| HCN Channels | ||||
| Target | Gene | Disorder | Cell Type | |
| HCN1 | HCN1 | - | HEK 293 | |
| HCN2 | HCN2 | - | HEK 293 | |
| HCN2 (rat) | HCN2 | - | HEK 293 | |
| HCN4 | HCN4 | - | HEK 293 | |
| HCN4 (rat) | HCN4 | - | HEK 293 | |
| Sodium Channels | ||||
| Target | Gene | Disorder | Cell Type | |
| NaV1.1 | SCN1A | - | CHO | |
| NaV1.2 | SCN2A | - | CHO | |
| NaV1.3 | SCN3A | Epilepsy / Pain | CHO | |
| NaV1.4 | SCN4A | - | HEK 293 | |
| NaV1.4 | SCN4A | - | CHO | |
| NaV1.5 | SCN5A | LQT Syndrome 3 | HEK | |
| NaV1.5 | SCN5A | LQT Syndrome 3 | HEK | |
| NaV1.5 duo | SCN5A | LQT Syndrome 3 | CHO | |
| NaV1.5 big late | SCN5A L409C/A410W | LQT Syndrome 3 | HEK 293 | |
| NaV1.5 ΔKPQ | SCN5A ΔKPQ | LQT Syndrome 3 | HEK | |
| NaV1.6 | SCN8A | - | CHO | |
| NaV1.7 | SCN9A | - | CHO | |
| NaV1.7 | SCN9A | - | CHO | |
| NaV1.8 | SCN10A/SCN3B | - | CHO | |
| NaV1.9 | SCN11A | - | HEK | |
|
Calcium Channels |
||||
|
Target
|
Gene | Disorder | Cell Type | |
| CaV1.2 | CACNA1C/CACNB2/ CACNA2D | - | HEK 293 | |
| CaV3.1 | CACNA1G | - | CHO | |
| CaV3.2 | CACNA1H | - | HEK 293 | |
| CaV3.3 | CACNA1I | - | HEK 293 | |
| CaV3.3 | CACNA1I | - | CHO | |
|
Chloride Channels |
||||
| Target | Gene | Disorder | Cell Type | |
| CFTR | CFTR | - | CHO | |
| CFTR | CFTR | - | HEK 293 | |
| ClC-1 | CLCN1 | - | HEK 293 | |
| ClC-1 | CLCN1 | - | CHO | |
|
TRP Channels |
||||
| Target | Gene | Disorder | Cell Type | |
| TRPA1 | TRPA1 | - | HEK 293 | |
| TRPA1 | TRPA1 | - | CHO | |
| TRPV1 | TRPV1 (VR1) | - | CHO | |
| TRPV1 (mouse) | TRPV1 (VR1) | - | CHO | |
| TRPV3 | TRPV3 | Olmsted syndrom | CHO | |
| TRPV3 (mouse) | TRPV3 | Olmsted syndrom | CHO | |
| TRPV4 | TRPV4 | Dwarfism, Neuropathy | HEK 293 | |
| TRPV4 (mouse) | TRPV4 | Dwarfism, Neuropathy | CHO | |
| TRPM4 | TRPM4 | - | CHO | |
| TRPM8 | TRPM8 | Pain sensation | HEK 293 | |
| 配体门控类 | ||||
| GABAA Receptors | ||||
| Target | Gene | Disorder | Cell Type | |
| GABA α1β2γ2 | GABRA1 / GABRB2 / GABRG2 | - | CHO | |
| GABA α2β2γ2 | GABRA2 / GABRB2 / GABRG2 | - | HEK | |
|
Glutamate Receptors |
||||
| Target | Gene | Disorder | Cell Type | |
| Kainate K2 | GRIK2 | - | CHO | |
| Kainate K2 | GRIK2 | - | HEK 293 | |
| NMDAR1 | GRIN1 | Mental retardation | CHO | |
| NMDA 1/2A | GRIN1/GRIN2A | Epilepsy | HEK 293 | |
| NMDA 1/2B | GRIN1/GRIN2B | Depression | HEK 293 | |
| NMDA 1/2D | GRIN1/GRIN2D | - | HEK 293 | |
| Acetylcholine Receptors | ||||
| Target | Gene | Disorder | Cell Type | |
| nAChR α4β2 | CHRNA4 / CHRNB2 | - | CHO | |
|
P2X Receptors |
||||
| Target | Gene | Disorder | Cell Type | |
| P2X1 | P2rx1 | - | CHO | |
| P2X2 | P2rx2 | - | CHO | |
| P2X2/3 | P2rx2/P2rx3 | - | CHO | |
| P2X3 | P2rx3 | - | CHO | |
| P2X4 | P2rx4 | - | HEK 293 | |
| P2X7 | P2rx7 | - | HEK 293 | |
| Glycine Receptors | ||||
| Target | Gene | Disorder | Cell Type | |
| GlyRα1 (h) | GLRA1 | - | CHO | |
| GlyRα2 (r) | GLRA2 | - | CHO | |
| GlyRα3 (h) | GLRA3 | Pain sensation | HEK 293 | |
| GlyRα3 (h) | GLRA3 | Pain sensation | CHO | |
| GlyRα3 (r) | GLRA3 | Pain sensation | CHO | |
| Serotonine Receptors | ||||
| Target | Gene | Disorder | Cell Type | |
| 5HT3A | 5HT3A | - | CHO | |
|
Acid sensing Receptors |
||||
| Target | Gene | Disorder | Cell Type | |
| ASIC1 isoform a | ACCN2 | - | CHO | |
| ASIC1 isoform b | ACCN2 | - | CHO | |
| ASIC1 isoform c | ACCN2 | - | CHO | |
| ASIC3 | ACCN3 | - | CHO | |
|
其他通道 |
||||
| Target | Gene | Disorder | Cell Type | |
| VDAC | VDAC1 | - | CHO | |
| PEPT1 | SLC15A1 | - | MDCK | |
| Stargazin | CACNG2 | Seizure disorders | HEK 293 | |
公司简介
上海神思药得科技有限公司专注于神经电生理与药物研发及表征相关科研设备和技术服务。提供场电位、手动与自动膜片钳、多电极阵列、细胞培养与监测、原子力显微镜、石英晶体微天平等多种电生理与表征精密仪器与配套试剂耗材。与国内多所高校及专业实验技术服务机构合作，提供全套证书与授权的稳定表达离子通道细胞系，以及基于离子通道的高通量药物筛选和临床前心脏安全性评价服务；神经疾病模型及相关电生理科研服务；iPSC诱导多能干细胞及相关服务。
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