alpha-红没药醇
基本信息
产品名称：
alpha-红没药醇
英文名称：
(±)-α-Bisabolol
国产/进口：
进口
产地/品牌：
美国/TargetMol
型号：
参考报价：
面议
销售商：
总点击数：
37
更新日期：
2025-05-14
产品类别：
性能参数
Product Introduction
Bioactivity
英文名: (±)-α-Bisabolol
描述: (±)-α-Bisabolol (Bisabolol) 是一种从洋甘菊、念珠菌树等植物精油中提取的倍半萜烯醇，是一种天然防腐剂，具有舒缓、抗刺激、抗炎、抗氧化和抗癌活性。(±)-α-Bisabolol 通过诱导细胞周期停滞、线粒体死亡和抑制 PI3K/Akt 信号通路来发挥作用，对 A549 NSC-LC 细胞产生抗癌作用 (IC50 = 15 μM)。(±)-α-Bisabolol 能强效诱导胶质瘤细胞凋亡。
体外活性: Under resting tonus, (–)-a-bisabolol (30–300 ?mol/L) relaxed duodenal strips. Contracting endothelium-intact aortic rings and urinary bladder strips, and relaxing these tissues at higher concentrations (600–1000 ?mol/L). In preparations precontracted either electromechanically (by 60 mmol/L K+) or pharmacomechanically (by phenylephrine or carbachol), (–)-a-bisabolol showed only relaxing properties. [1]
体内活性: (-)-α-Bisabolol (100-200 mg/kg; p.o.; one day before and 1 h after pMCAO; once daily for the following five days; mice) significantly reduces the infarcted area and neurological deficits caused by pMCAO. (?)-α-bisabolol can exert anti-inflammatory effects by reducing astrogliosis, MPO activity, and TNF-α and iNOS production.[1] (–)-a-bisabolol attenuated the increased responses of carbachol in tracheal rings of ovalbumin-sensitized rats challenged with ovalbumin, but was without effect in the decreased responsiveness of urinary bladder strips in mice treated with ifosfamide. (–)-a-bisabolol may be an inhibitor of voltage-dependent Ca2+ channels.[2]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 90.0 mg/mL (404.7 mM)
关键字: a-Bisabolol | alpha-Bisabolol | α-Bisabolol
相关产品: JIB-04 | ATH686 | Suberoyl bis-hydroxamic acid | Rotundic acid | O6-Benzylguanine | Prosapogenin A | Stattic | SC-43 | LY2857785 | W-7 hydrochloride
Bioactivity
英文名: (±)-α-Bisabolol
描述: (±)-α-Bisabolol (Bisabolol) 是一种从洋甘菊、念珠菌树等植物精油中提取的倍半萜烯醇，是一种天然防腐剂，具有舒缓、抗刺激、抗炎、抗氧化和抗癌活性。(±)-α-Bisabolol 通过诱导细胞周期停滞、线粒体死亡和抑制 PI3K/Akt 信号通路来发挥作用，对 A549 NSC-LC 细胞产生抗癌作用 (IC50 = 15 μM)。(±)-α-Bisabolol 能强效诱导胶质瘤细胞凋亡。
体外活性: Under resting tonus, (–)-a-bisabolol (30–300 ?mol/L) relaxed duodenal strips. Contracting endothelium-intact aortic rings and urinary bladder strips, and relaxing these tissues at higher concentrations (600–1000 ?mol/L). In preparations precontracted either electromechanically (by 60 mmol/L K+) or pharmacomechanically (by phenylephrine or carbachol), (–)-a-bisabolol showed only relaxing properties. [1]
体内活性: (-)-α-Bisabolol (100-200 mg/kg; p.o.; one day before and 1 h after pMCAO; once daily for the following five days; mice) significantly reduces the infarcted area and neurological deficits caused by pMCAO. (?)-α-bisabolol can exert anti-inflammatory effects by reducing astrogliosis, MPO activity, and TNF-α and iNOS production.[1] (–)-a-bisabolol attenuated the increased responses of carbachol in tracheal rings of ovalbumin-sensitized rats challenged with ovalbumin, but was without effect in the decreased responsiveness of urinary bladder strips in mice treated with ifosfamide. (–)-a-bisabolol may be an inhibitor of voltage-dependent Ca2+ channels.[2]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 90.0 mg/mL (404.7 mM)
关键字: a-Bisabolol | alpha-Bisabolol | α-Bisabolol
相关产品: JIB-04 | ATH686 | Suberoyl bis-hydroxamic acid | Rotundic acid | O6-Benzylguanine | Prosapogenin A | Stattic | SC-43 | LY2857785 | W-7 hydrochloride
公司简介
TargetMol（陶术）作为一家全球性的生物医药领域高科技企业，我们致力于为高校、研究所、医院、企业等各类生物医药研发机构提供优质的产品和服务，为全球医药科学家更高效地完成科研工作助力。可提供20,000+种 抑制剂和激动剂 、800+种 化合物库 、19,000+种 天然产物 ，以及9,000+种 重组蛋白 、多种 多肽 、抗体 和 生命科学试剂盒 等。此外，在上海，TargetMol研发中心配备了 CADD & AIDD研究中心、药理实验室和药物化学合成 平台三大技术中心，可提供虚拟筛选、化合物活性测试、分子间结合力检测和化合物结构优化等技术服务，多方位满足用户的研发需求。
售后服务
相关视频
暂无
资料下载
暂无
联系方式
| 单位名称： |
|
详细地址：
静安区江场三路238号
|
|
qq：
2881954871
|
|
联系电话：
021-33632979
|
| Email： |
