MPM多臂智能脑图谱立体定位系统
基本信息
产品名称：
MPM多臂智能脑图谱立体定位系统
英文名称：
MPM Multi-Arm Intelligent Brain Atlas Stereotaxic System
国产/进口：
进口
产地/品牌：
New Scale
型号：
MPM
参考报价：
销售商：
总点击数：
38
更新日期：
2025-05-14
产品类别：
性能参数
MPM智能定位系统是Neuropixels电极官方推荐的专用电极植入平台，为需要一次植入多支电极、光纤或注射针的实验专门设计。Neuropixels+MPM是目前在清醒活动动物上进行多脑区、深部、高通量、单细胞精度的电信号采集热门技术。
如果您对特定脑区感兴趣，请告诉我们，我们将为您量身定制并展示最优的植入路径，我们的技术确保即使是首次接触Neuropixels植入的用户，也能迅速且精确地达到目标脑区（联系方式见文末）。
Neuropixels
Neuropixels是目前全球流行的基于CMOS芯片的在体多通道记录设备。不同于传统的微丝电极和硅电极，Neuropixels在探针部位就已经完成信号的放大和数模转换，使得采集信号更稳定；能够集成更多记录位点和记录通道。
经典的Neropixels 1.0（NP 1.0）探针在10mm长的电极柄上均匀分布了960个记录位点，这一独特的设计非常适合贯穿多个脑区，记录大量脑区的神经元放电。
新推出的Neuropixels 2.0（NP 2.0）探针，使Neuropixels的功能进一步升级，每个探针拥有四个电极柄，每根电极柄的记录位点数量增加到1280个，因此每根探针有5120个记录位点，此外，探针和headstage的体积更小重量更轻，更适合在自由活动的动物上进行数据采集。
MPM
想要最大程度发挥Neuropixels全脑大尺度神经检测的优势，就不得不提New Scale Technologies公司研发的高精度多探针操纵器系统（Multiprobe Manipulator, MPM）。
2023年，骆利群教授在《Nature》杂志上发表的论文就用到了Neuropixels+MPM的组合。研究团队在一个动物上同时植入四根探针，通过多次植入，实现了对全脑多个脑区的广泛覆盖。通过深入分析各脑区的单细胞放电活动和动物行为间的关系，揭示了大脑编码冲突性选择的内在机制。
为什么需要MPM
Neuropixels虽然功能强大，但是利用传统的立体定位仪进行电极的植入很难发挥Neuropixels的优势，并且会带来很多问题。
1、Neuropixels电极比普通电极长很多，并且要求包括电极尖端在内的整根电极柄都能植入至对应的脑区，对定位精度的要求比传统电极高出很多，传统立体定位仪的精度很难达到要求；
2、Neuropixels电极的高效使用方式，通常需要使其一次性穿过准备记录的多个脑区核团，植入的路径通常并不垂直于颅顶面，传统的立体定位仪在进行XZ和YZ两个面均有角度的植入时，需要复杂的计算，实现难度往往很大；
3、为实现更多的通道数，很多实验室都会设计一次植入多根电极，并且要保证这些电极互相不会产生干扰，用传统立体定位仪很难实现；
4、Neuropixels电极十分昂贵，如何保证其植入的成功率，并减少电极的损伤，是开展实验前需要认真考虑的实际问题。
MPM的优势
作为Neuropixels官方推荐的植入平台，MPM解决了Neuropixels探针植入过程中的很多难点，包括：多电极植入、倾斜植入、准确性、稳定性和安全性等。
1、支持多达八根探针的同时植入。
2、独一无二的虚拟植入系统。MPM开发了其最有特色的虚拟植入软件系统，很好地解决了多探针植入轨迹规划的难题。
首先在NTE轨道规划软件中设计探针植入的位置和深度，使得探针可以尽可能多地贯穿感兴趣脑区。
结合NTE软件中获得的参数，在虚拟植入系统中反复调试最佳的植入轨迹，并获得合适的平台参数。这使得实际植入过程变得十分便捷，并可以有效避免探针碰撞引起的损伤。
3、 统一坐标系，前后囟校准。
MPM软件针对每一根探针可进行前后囟校准，并建立统一的坐标系，无需担心动物头部的轻微歪斜，进一步确保倾斜植入的准确性。
4、提供多种移动探针的便捷方法。可同时使用摇杆、手柄和软件控制微操，使用更自由便捷。
5、实时呈现探针植入全过程。植入系统与NTE轨道设计软件联动，可实时看到每根探针接触到的脑区，结合实时电生理信号，帮助判断植入准确性。
MPM Multi-Arm Intelligent Brain Atlas Stereotaxic System
The MPM Intelligent Positioning System is the officially recommended platform for Neuropixels electrode implantation, specifically designed for experiments requiring the simultaneous insertion of multiple electrodes, optical fibers, or injection needles. Neuropixels + MPM is currently a leading technology for high-throughput, single-cell precision electrophysiological recordings across multiple deep brain regions in awake, behaving animals.
If you are interested in specific brain regions, let us know—we will customize and present the optimal implantation path for you. Our technology ensures that even first-time users of Neuropixels can achieve precise targeting quickly (contact details at the end).
---
Neuropixels
Neuropixels is a globally popular CMOS-based in vivo multichannel recording device. Unlike traditional microwire or silicon electrodes, Neuropixels performs signal amplification and analog-to-digital conversion directly on the probe, resulting in more stable signal acquisition and enabling higher-density recording sites and channels.
The classic Neuropixels 1.0 (NP 1.0) probe features 960 recording sites evenly distributed along a 10mm shank, making it ideal for spanning multiple brain regions and capturing neuronal activity across large-scale neural circuits.
The newly released Neuropixels 2.0 (NP 2.0) further enhances functionality, with four shanks per probe and 1,280 recording sites per shank (5,120 total per probe). Additionally, the probe and headstage are smaller and lighter, making them better suited for freely moving animals.
---
MPM
To fully leverage Neuropixels' large-scale, whole-brain neural recording capabilities, the Multiprobe Manipulator (MPM) system, developed by New Scale Technologies, is indispensable.
In 2023, Professor Liqun Luo published a Nature paper using Neuropixels + MPM. The team implanted four probes simultaneously in a single animal, achieving extensive coverage across multiple brain regions. By analyzing single-neuron activity and behavior, they uncovered neural mechanisms underlying conflict-driven decision-making.
---
Why MPM?
While Neuropixels is powerful, traditional stereotaxic systems struggle to maximize its potential and introduce several challenges:
1. Higher precision requirements – Neuropixels probes are much longer than conventional electrodes, requiring the entire shank (including the tip) to reach target regions accurately. Traditional stereotaxic systems often lack the necessary precision.
2. Complex trajectory planning – Optimal Neuropixels use often requires oblique insertions through multiple brain regions. Traditional systems struggle with dual-plane angle adjustments (XZ & YZ), making implantation difficult.
3. Multi-probe coordination – Many labs implant multiple probes simultaneously to increase channel count, but avoiding probe collisions is nearly impossible with traditional systems.
4. Probe safety – Neuropixels probes are expensive. Ensuring high implantation success rates and minimizing damage are critical practical concerns.
---
MPM Advantages
As the official recommended implantation platform for Neuropixels, MPM overcomes key challenges: multi-probe insertion, angled trajectories, accuracy, stability, and safety.
1. Supports up to 8 simultaneous probe insertions.
2. Virtual Implantation System – MPM’s unique software solves multi-probe trajectory planning:
- Design probe positions and depths in NTE Track Planning Software to maximize coverage of target regions.
- Simulate and refine trajectories in the Virtual Implantation System, ensuring optimal parameters before real insertion.
- Prevents probe collisions and minimizes damage.
3. Unified Coordinate System & Bregma-Lambda Calibration – MPM software calibrates each probe to bregma-lambda coordinates, compensating for minor head tilts and ensuring accurate oblique insertions.
4. Flexible Probe Control – Adjust probes via joystick, hand controller, or software for seamless operation.
5. Real-Time Implantation Monitoring – The system integrates with NTE Track Software, displaying real-time probe locations and brain region contacts, while live electrophysiology signals verify accuracy.
---
Let us help you unlock the full potential of large-scale, high-yield neural recordings with Neuropixels + MPM! (Contact us for details.)
联系我们 Contact Us
如果您想了解我们产品的更多信息，欢迎拨打礼智官方客服电话18260099904、微信扫码公众号或者添加礼智小客服咨询。
If you'd like to learn more about our products, feel free to:
- Call our official customer service line: 18260099904
- Scan the QR code to visit our WeChat official account
- Add "Lizhi Assistant" on WeChat for inquiries.
如果您对特定脑区感兴趣，请告诉我们，我们将为您量身定制并展示最优的植入路径，我们的技术确保即使是首次接触Neuropixels植入的用户，也能迅速且精确地达到目标脑区（联系方式见文末）。
Neuropixels
Neuropixels是目前全球流行的基于CMOS芯片的在体多通道记录设备。不同于传统的微丝电极和硅电极，Neuropixels在探针部位就已经完成信号的放大和数模转换，使得采集信号更稳定；能够集成更多记录位点和记录通道。
经典的Neropixels 1.0（NP 1.0）探针在10mm长的电极柄上均匀分布了960个记录位点，这一独特的设计非常适合贯穿多个脑区，记录大量脑区的神经元放电。
新推出的Neuropixels 2.0（NP 2.0）探针，使Neuropixels的功能进一步升级，每个探针拥有四个电极柄，每根电极柄的记录位点数量增加到1280个，因此每根探针有5120个记录位点，此外，探针和headstage的体积更小重量更轻，更适合在自由活动的动物上进行数据采集。
MPM
想要最大程度发挥Neuropixels全脑大尺度神经检测的优势，就不得不提New Scale Technologies公司研发的高精度多探针操纵器系统（Multiprobe Manipulator, MPM）。
2023年，骆利群教授在《Nature》杂志上发表的论文就用到了Neuropixels+MPM的组合。研究团队在一个动物上同时植入四根探针，通过多次植入，实现了对全脑多个脑区的广泛覆盖。通过深入分析各脑区的单细胞放电活动和动物行为间的关系，揭示了大脑编码冲突性选择的内在机制。
为什么需要MPM
Neuropixels虽然功能强大，但是利用传统的立体定位仪进行电极的植入很难发挥Neuropixels的优势，并且会带来很多问题。
1、Neuropixels电极比普通电极长很多，并且要求包括电极尖端在内的整根电极柄都能植入至对应的脑区，对定位精度的要求比传统电极高出很多，传统立体定位仪的精度很难达到要求；
2、Neuropixels电极的高效使用方式，通常需要使其一次性穿过准备记录的多个脑区核团，植入的路径通常并不垂直于颅顶面，传统的立体定位仪在进行XZ和YZ两个面均有角度的植入时，需要复杂的计算，实现难度往往很大；
3、为实现更多的通道数，很多实验室都会设计一次植入多根电极，并且要保证这些电极互相不会产生干扰，用传统立体定位仪很难实现；
4、Neuropixels电极十分昂贵，如何保证其植入的成功率，并减少电极的损伤，是开展实验前需要认真考虑的实际问题。
MPM的优势
作为Neuropixels官方推荐的植入平台，MPM解决了Neuropixels探针植入过程中的很多难点，包括：多电极植入、倾斜植入、准确性、稳定性和安全性等。
1、支持多达八根探针的同时植入。
2、独一无二的虚拟植入系统。MPM开发了其最有特色的虚拟植入软件系统，很好地解决了多探针植入轨迹规划的难题。
首先在NTE轨道规划软件中设计探针植入的位置和深度，使得探针可以尽可能多地贯穿感兴趣脑区。
结合NTE软件中获得的参数，在虚拟植入系统中反复调试最佳的植入轨迹，并获得合适的平台参数。这使得实际植入过程变得十分便捷，并可以有效避免探针碰撞引起的损伤。
3、 统一坐标系，前后囟校准。
MPM软件针对每一根探针可进行前后囟校准，并建立统一的坐标系，无需担心动物头部的轻微歪斜，进一步确保倾斜植入的准确性。
4、提供多种移动探针的便捷方法。可同时使用摇杆、手柄和软件控制微操，使用更自由便捷。
5、实时呈现探针植入全过程。植入系统与NTE轨道设计软件联动，可实时看到每根探针接触到的脑区，结合实时电生理信号，帮助判断植入准确性。
MPM Multi-Arm Intelligent Brain Atlas Stereotaxic System
The MPM Intelligent Positioning System is the officially recommended platform for Neuropixels electrode implantation, specifically designed for experiments requiring the simultaneous insertion of multiple electrodes, optical fibers, or injection needles. Neuropixels + MPM is currently a leading technology for high-throughput, single-cell precision electrophysiological recordings across multiple deep brain regions in awake, behaving animals.
If you are interested in specific brain regions, let us know—we will customize and present the optimal implantation path for you. Our technology ensures that even first-time users of Neuropixels can achieve precise targeting quickly (contact details at the end).
---
Neuropixels
Neuropixels is a globally popular CMOS-based in vivo multichannel recording device. Unlike traditional microwire or silicon electrodes, Neuropixels performs signal amplification and analog-to-digital conversion directly on the probe, resulting in more stable signal acquisition and enabling higher-density recording sites and channels.
The classic Neuropixels 1.0 (NP 1.0) probe features 960 recording sites evenly distributed along a 10mm shank, making it ideal for spanning multiple brain regions and capturing neuronal activity across large-scale neural circuits.
The newly released Neuropixels 2.0 (NP 2.0) further enhances functionality, with four shanks per probe and 1,280 recording sites per shank (5,120 total per probe). Additionally, the probe and headstage are smaller and lighter, making them better suited for freely moving animals.
---
MPM
To fully leverage Neuropixels' large-scale, whole-brain neural recording capabilities, the Multiprobe Manipulator (MPM) system, developed by New Scale Technologies, is indispensable.
In 2023, Professor Liqun Luo published a Nature paper using Neuropixels + MPM. The team implanted four probes simultaneously in a single animal, achieving extensive coverage across multiple brain regions. By analyzing single-neuron activity and behavior, they uncovered neural mechanisms underlying conflict-driven decision-making.
---
Why MPM?
While Neuropixels is powerful, traditional stereotaxic systems struggle to maximize its potential and introduce several challenges:
1. Higher precision requirements – Neuropixels probes are much longer than conventional electrodes, requiring the entire shank (including the tip) to reach target regions accurately. Traditional stereotaxic systems often lack the necessary precision.
2. Complex trajectory planning – Optimal Neuropixels use often requires oblique insertions through multiple brain regions. Traditional systems struggle with dual-plane angle adjustments (XZ & YZ), making implantation difficult.
3. Multi-probe coordination – Many labs implant multiple probes simultaneously to increase channel count, but avoiding probe collisions is nearly impossible with traditional systems.
4. Probe safety – Neuropixels probes are expensive. Ensuring high implantation success rates and minimizing damage are critical practical concerns.
---
MPM Advantages
As the official recommended implantation platform for Neuropixels, MPM overcomes key challenges: multi-probe insertion, angled trajectories, accuracy, stability, and safety.
1. Supports up to 8 simultaneous probe insertions.
2. Virtual Implantation System – MPM’s unique software solves multi-probe trajectory planning:
- Design probe positions and depths in NTE Track Planning Software to maximize coverage of target regions.
- Simulate and refine trajectories in the Virtual Implantation System, ensuring optimal parameters before real insertion.
- Prevents probe collisions and minimizes damage.
3. Unified Coordinate System & Bregma-Lambda Calibration – MPM software calibrates each probe to bregma-lambda coordinates, compensating for minor head tilts and ensuring accurate oblique insertions.
4. Flexible Probe Control – Adjust probes via joystick, hand controller, or software for seamless operation.
5. Real-Time Implantation Monitoring – The system integrates with NTE Track Software, displaying real-time probe locations and brain region contacts, while live electrophysiology signals verify accuracy.
---
Let us help you unlock the full potential of large-scale, high-yield neural recordings with Neuropixels + MPM! (Contact us for details.)
联系我们 Contact Us
如果您想了解我们产品的更多信息，欢迎拨打礼智官方客服电话18260099904、微信扫码公众号或者添加礼智小客服咨询。
If you'd like to learn more about our products, feel free to:
- Call our official customer service line: 18260099904
- Scan the QR code to visit our WeChat official account
- Add "Lizhi Assistant" on WeChat for inquiries.
公司简介
礼智生物科技有限公司成立于2011年，是神经科学领域专业的科研仪器及技术服务供应商，在香港、上海、北京、广州、南京、沈阳等地均设有分公司。
公司拥有独家代理的和自研开发的多款神经科学领域前沿高科技产品：
礼智在售产品:
🔷 fUS清醒活动动物的全脑实时功能成像及多脏器血流成像
🔷 唯一可构建体外AI的单细胞分辨率MEA细胞电生理成像
🔷 家喻户晓的Neuropixels数字神经电极在体多通道电生理
🔷 大空间、快扫描、可结合电生理记录的双光子显微镜
🔷 无线光遗传、无线光纤记录、无线在体多通道、无线EEG等多款特色无线记录系统
🔷多色多通道光纤记录、Miniscope、双色大视野荧光显微镜等多款在体钙成像系统
🔷 超高性价比的在体多通道电生理系统及配套电极
🔷 在体化学物质及神经递质实时检测系统
🔷 全自动脑片膜片钳、迷你膜片钳、人工脂双层等电生理系统
🔷 软、硬组织透明化、光片显微镜
🔷 气浮笼、隔音箱、任务训练等行为学设备
🔷 桌面式及大空间PET/CT系统
🔷 人工授精及胚胎自动注射系统
🔷 立体定位仪、麻醉机、自动化颅骨开窗等小动物手术设备
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