重组人ANGPTL4蛋白|ANGPTL4蛋白
基本信息
产品名称：
重组人ANGPTL4蛋白|ANGPTL4蛋白
英文名称：
Human ANGPTL4 Protein, His Tag
国产/进口：
国产
产地/品牌：
卡梅德生物科技（天津）有限公司
型号：
KMP2268
参考报价：
640
销售商：
总点击数：
1090
更新日期：
2025-08-19
产品类别：
性能参数
产品编号: KMP2268
产品名称: Human ANGPTL4 Protein, His Tag
中文名称: 重组人ANGPTL4蛋白
中文全称: 重组人血管生成素样蛋白4蛋白
关键词: 血管生成素样蛋白4, Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, Angptl4, Farp, Fiaf, Ng27, Human ANGPTL4 Protein, His Tag, Recombinant Protein, KMP2268
物种: Human
宿主: HEK293 Cells
规格: 50ug, 100ug, 200ug
纯化方式: Affinity purification
纯度: >95% as determined by SDS-PAGE
内毒素水平: <1.0 EU/ug determined by the LAL method
缓冲体系: PBS, pH7.4
Uniprot: Q9BY76
SDS-PAGE: KMP2268 SDS-PAGE image1.png
功能: 1.Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. 2.May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. 3.Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro).
4.Depending on context, may modulate tumor-related angiogenesis (By similarity).
产品背景: Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity(By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
说明: This product is for research use only.
具体参数链接: https://www.kmdbioscience.cn/
参考文献: 1.Cancer Res. 63:6651-6657 (2003)
2.Circ. Res. 99:1207-1215 (2006)
3.J. Biol. Chem. 284:13213-13222 (2009)
4.J. Biol. Chem. 286:15747-15756 (2011)
5.Elife 5:0-0 (2016)
6.Proc. Natl. Acad. Sci. U.S.A. 115:E6020-E6029 (2018)
7.Nat. Commun. 9:2252-2252 (2018)
产品名称: Human ANGPTL4 Protein, His Tag
中文名称: 重组人ANGPTL4蛋白
中文全称: 重组人血管生成素样蛋白4蛋白
关键词: 血管生成素样蛋白4, Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, Angptl4, Farp, Fiaf, Ng27, Human ANGPTL4 Protein, His Tag, Recombinant Protein, KMP2268
物种: Human
宿主: HEK293 Cells
规格: 50ug, 100ug, 200ug
纯化方式: Affinity purification
纯度: >95% as determined by SDS-PAGE
内毒素水平: <1.0 EU/ug determined by the LAL method
缓冲体系: PBS, pH7.4
Uniprot: Q9BY76
SDS-PAGE: KMP2268 SDS-PAGE image1.png
功能: 1.Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. 2.May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. 3.Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro).
4.Depending on context, may modulate tumor-related angiogenesis (By similarity).
产品背景: Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity(By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
说明: This product is for research use only.
具体参数链接: https://www.kmdbioscience.cn/
参考文献: 1.Cancer Res. 63:6651-6657 (2003)
2.Circ. Res. 99:1207-1215 (2006)
3.J. Biol. Chem. 284:13213-13222 (2009)
4.J. Biol. Chem. 286:15747-15756 (2011)
5.Elife 5:0-0 (2016)
6.Proc. Natl. Acad. Sci. U.S.A. 115:E6020-E6029 (2018)
7.Nat. Commun. 9:2252-2252 (2018)
公司简介
天津卡梅德科技发展有限公司不断致力于成为领先的药物抗体发现及相关配套服务提供商。我们以技术研发为核心，为全球科学家和研究机构提供高品质的CRO（合同研究组织）服务，旨在推动医药科技的发展和创新。
作为一家高新技术企业，我们拥有国家专利试点单位和实验室ISO9001:2015质量管理体系认证，并荣获超过30项专利和4项注册商标。卡梅德生物的技术服务团队超过90%的人员为硕士以上学历，我们每年为国内外各类研究机构、医院、制药公司和生物公司提供近千件项技术服务咨询、方案设计以及项目交付。我们的核心服务平台包括抗体药物发现平台、抗体工程改造平台、稳定细胞系构建与菌株开发工艺平台、重组抗体和重组蛋白表达和纯化平台等。
除了专业的技术服务，卡梅德生物坚守着诚信、创新和卓越的价值观。我们将持续不断的技术创新视为公司发展的动力，致力于为客户提供最优质的解决方案。
天津卡梅德科技发展将继续坚持技术创新、服务卓越的理念，努力成为行业的引领者，为人类健康事业贡献更多的力量。
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