甲磺酸CP 101606
CP 101606 mesylate -
Traxoprodil mesylate
CAS 189894-57-3 (MsOH)
134234-12-1 (free base)
C20H25NO3.CH4O3S
Purity: 99% (optically pure)
Soluble in water and DMSO
|
Biological Activity:
Potent and NR2B selective antagonist of NMDA glutamate receptors; the mesylate salt is the optimal water-soluble drug form.
References: K Taniguchi etal. Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist. Br. J. Pharmacol. 1997, 122, 809–812.
FS. Menniti etal. CP-101,606: An NR2B-Selective NMDA Receptor Antagonist. CNS Drug Rev. 1998, 4(4), 307-322.
L Yurkewicz etal. The effect of the selective NMDA receptor antagonist traxoprodil in the treatment of traumatic brain injury. J. Neurotrauma. 2005, 22(12), 1428-43.
JG Nutt etal. Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and parkinsonist. Mov. Disord. 2008, 23(13), 1860-1866.
Chemical Name:
|
| CP 101606 | NMDA antagonist | Axon Medchem | Traxoprodil mesylate | Axon 1406 | CP101606 - CP-101,606 supplier |
|
Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis. |
| 单位名称: |
|
详细地址:
北京市海淀区澄湾街19号院大北农凤凰国际创新园5号楼
|
|
qq:
2477120690
|
| 联系电话: |
| Email: |