微型生物探针 液相氮化硅探针BL-AC40TS

High resonance at around 110 kHz in air and 25 kHz in water while its small spring constant of around 0.1 N/m. The high resonance cantilever is worth while scanning fast to shorten the data acquisition time and to make smooth and quick operation in magnifying a target area on the sample surface.

Sharpened silicon tips with its tip radius of 10 nm (typ.)

• The short cantilevers with its length of around 40 micro meters become advantageous for high sensitivity of optical beam deflection sensors in AFMs.
• The small area lever responds quickly to shape change of bio-moleculars with short relaxation time.
• Less noise in thermal vibration spectrum

Silicon nitride cantilever, minimized its auto fluorescence, would not become an obstacle in fluorescent observation.

Each cantilever chip is isolated in the case. The chips can be attached to the AFM instrument as soon as the case is open.

Due to the sharp tip, 'BioLever mini' is recommended for turning image resolution up another notch in studying of bio moleculers, DNA strands etc..

The long tip works to the advantage of AFM imaging of relatively thick samples like bio cells.

Bio samples like DNA strands scattered on mica substrate, would not be uniform in density over the substrate. Then, in the observation of such a sample, number of scanning over the sample would be carried out from large area to small area. The series of observation steps, it would be repeated until clearly revealing a point of interests at a certain magnification. However, previous cantilevers in large size cannot scan fast in water because of the large damping in water. What is longing for among many operators, is shorten the time for searching to confirm whether scan area includes the target DNAs. In the early steps of observation series, fast imaging is much benefitial rather than high resolution imaging. A cantilever with high resonance in water like this 'BioLever mini' would be required for fast scanning.

'BioLever mini' (left image) less emitted autofluorescence light than conventional silicon nitride cantilever (right image) while observing fluorescence from stained bio samples. 'BioLever mini' less diturbs fluorescence optical microscopy than conventional soft cantilever probes.
 

1.https://www.nature.com/articles/s41598-021-92365-y   BL-AC10DS-A2   活细胞延时成像 力学

相关案例：

2.https://www.nature.com/articles/s42003-021-02388-4     BL-AC10DS -A2   病毒因子RNA 合成

3.https://www.nature.com/articles/srep07818    BL-AC10DS-A2   机械震荡

4.https://www.nature.com/articles/s41467-021-25023-6     BL-AC40TS-C2    DNA记忆堆栈

5.https://www.nature.com/articles/ncomms11566      BL-AC40TS-C2      水凝胶AFM纳米探针

6.https://www.nature.com/articles/s41598-021-91371-4       BL-AC40TS-C2     SARS-CoV-2 包膜病

特别提示：
近期市场出现不良销售代理商以OPUS的探针冒充Olympus的针尖，此行为不仅造成市场混乱，更给科研工作者带来了严重的实验数据及过程造成了无法弥补的结果，希望各位用户从正规渠道购买，如您发现有任何问题，欢迎来电咨询了解!

自2014年始北京创美伟业科技公司的探针业务均由上海分公司上海寰太电子科技有限公司/上海展悦电子科技有限公司承办，请给各位新老客户谅解！我公司是Olympus的大陆唯一总代，更有Olympus日本工程师实时在线支持，免您后顾之忧！
年度特惠活动正在进行中，欢迎各实验室/课题组来电咨询了解，18017933200（微信同号）郑小姐