重组人组织型纤溶酶原激活剂(PLAT)

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产品名称：重组人组织型纤溶酶原激活剂(PLAT)
英文名称：Recombinant Human Tissue-type plasminogen activator
产品货号：JN1154
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser36-Pro562在C端含有His标签。

PLAT质量控制：＞95%(还原性SDS-PAGE)

PLAT制剂：冻干品

PLAT保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PLAT复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PLAT：
Tissue-type plasminogen activator (PLAT) is a protein that secretedinto extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-translational activation of growth factors. PLAT is found not only in the blood, where its primary function is as a thrombolytic enzyme, but also in the central nervous system (CNS). It participates in a number of physiological and pathological events in the CNS, as well as the role of neuroserpin as the natural regulator of PLATs activity in these processes. Increased or decreased activity of PLAT leads to hyperfibrinolysis or hypofibrinolysis, respectively. In addition, as a cytokine, PLAT plays a pivotal role in the pathogenesis of renal interstitial fibrosis through diverse mechanisms. Thus, as a fibrogenic cytokine, it promotes the progression of kidney diseases.

根据您的关注的重组人组织型纤溶酶原激活剂(PLAT)，重组人组织型纤溶酶原激活剂，重组组织型纤溶酶原激活剂，重组Tissue-type plasminogen activator，Recombinant Human Tissue-type plasminogen activator，重组人PLAT，重组人Tissue-type plasminogen activator，rhPLAT，重组PLAT，rPLAT，您可能还对以下产品有需求：
 

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关注重组人组织型纤溶酶原激活剂(PLAT)，重组人组织型纤溶酶原激活剂，重组组织型纤溶酶原激活剂，重组Tissue-type plasminogen activator，Recombinant Human Tissue-type plasminogen activator，重组人PLAT，重组人Tissue-type plasminogen activator，rhPLAT，重组PLAT，rPLAT的同时，为您推荐更多您可能感兴趣的产品：


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