抗MMAE鼠单克隆抗体-HRP标记
Anti-MMAE (Monomethyl Auristain E) antibody, mAb--HRP标记
抗MMAE鼠单克隆抗体-HRP标记
编号:YKMP18010H
货期:现货
Background
Monomethyl auristatin E (MMAE, vedotin) is a very potent antimitotic agent that inhibits cell division by blocking the polymerisation of tubulin. The family of auristatins are synthetic analogues of the antineoplastic natural product Dolastatin 10, ultrapotent cytotoxic microtubule inhibitors that are clinically used as payloads in antibody-drug conjugates. Antibody-drug conjugates enhance the antitumor effects of antibodies and reduce adverse systemic effects of highly potent cytotoxic agents.
Anti-MMAE (Monomethyl Auristain E) antibody, mAb
Monomethyl auristatin E (MMAE; SGD-1010) 是海兔毒素10的合成衍生物,通过抑制微管蛋白聚合而起到有效的有丝分裂抑制作用。MMAE广泛用作细胞毒性成分制作抗体-药物偶联物 (ADCs) 以治疗癌症。
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Anti-MMAE (Monomethyl Auristain E) antibody, mAb
抗MMAE鼠单抗
编号:YKMP18010
货期:现货