Rhodamine phalloidin罗丹明标记鬼笔环肽
基本信息
产品名称：
Rhodamine phalloidin罗丹明标记鬼笔环肽
英文名称：
Rhodamine phalloidin
国产/进口：
进口
产地/品牌：
Cytoskeleton
型号：
PHDR1
参考报价：
销售商：
总点击数：
8477
更新日期：
2025-09-23
产品类别：
性能参数
产品简介：
罗丹明鬼笔环肽是 F-肌动蛋白的高亲和力探针，由蘑菇毒素制成，与橙色荧光染料四甲基罗丹明 (TRITC) 偶联。 以纳米摩尔浓度使用时，鬼笔毒素是方便的探针，可用于对甲醛固定和打孔的组织切片、细胞培养物或无细胞实验体系中的 F-肌动蛋白进行标记、鉴别和定量。
Product Uses Include
- Stain F-actin in fixed cells
- Stabilize actin filaments in vitro
- Visualize actin filaments in vitro
Material
Phalloidin's usefulness as a laboratory tool is well established and lies in it's ability to inhibit microfilament de-polymerization. Thus, phalloidin stabilized microfilaments are used as substrates for the identification and characterization of the ever increasing number of microfilament associated proteins. In addition, rhodamine phalloidin can be used for staining the actin cytoskeleton in cells, and also as a fluorescent marker/stabilizer for microfilaments used in motility assays.
Phalloidin's usefulness as a laboratory tool is well established and lies in it's ability to inhibit microfilament de-polymerization. Thus, phalloidin stabilized microfilaments are used as substrates for the identification and characterization of the ever increasing number of microfilament associated proteins. In addition, rhodamine phalloidin can be used for staining the actin cytoskeleton in cells, and also as a fluorescent marker/stabilizer for microfilaments used in motility assays.
The rhodamine phalloidin is provided as a lyophilized powder. When reconstituted with 500 µl methanol, it is at 14 µM (200 x stock).
Purity
In keeping with our policy of providing only the highest quality products, we are now pleased to inform you that Cytoskeleton is offering rhodamine phalloidin at a chromatographic purity of >99%. This is the purest phalloidin commercially available for research use.
In keeping with our policy of providing only the highest quality products, we are now pleased to inform you that Cytoskeleton is offering rhodamine phalloidin at a chromatographic purity of >99%. This is the purest phalloidin commercially available for research use.
Biological Activity
We have determined that the microfilament stabilizing property of our product is equal or superior to any other commercially available phalloidins. Microfilaments in 70 nM phalloidin are stable at room temperature for over one week.
We have determined that the microfilament stabilizing property of our product is equal or superior to any other commercially available phalloidins. Microfilaments in 70 nM phalloidin are stable at room temperature for over one week.
Examples of publications where this product was used:
Chandhoke, S. K., Williams, M., Schaefer, E., Zorn, L. and Blystone, S. D. (2004). β3 integrin phosphorylation is essential for Arp3 organization into leukocyte αVβ3-vitronectin adhesion contacts. J. Cell Sci. 117, 1431-1441.
Chandhoke, S. K., Williams, M., Schaefer, E., Zorn, L. and Blystone, S. D. (2004). β3 integrin phosphorylation is essential for Arp3 organization into leukocyte αVβ3-vitronectin adhesion contacts. J. Cell Sci. 117, 1431-1441.
Chen, J., Fabry, B., Schiffrin, E. L. and Wang, N. (2001). Twisting integrin receptors increases endothelin-1 gene
Ezratty, E. J., Partridge, M. A. and Gundersen, G. G. (2005). Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat. Cell Biol. 7, 581-590.
Gomes, E. R., Jani, S. and Gundersen, G. G. (2005). Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell 121, 451-463.
Hsieh-Wilson, L. C., Benfenati, F., Snyder, G. L., Allen, P. B., Nairn, A. C. and Greengard, P. (2003). Phosphorylation of spinophilin modulates its interaction with actin filaments. J. Biol. Chem. 278, 1186-1194.
Qian, Y., Baisden, J. M., Cherezova, L., Summy, J. M., Guappone-Koay, A., Shi, X., Mast, T., Pustula, J., Zot, H. G., Mazloum, N. et al. (2002). PKC phosphorylation increases the ability of AFAP-110 to cross-
公司简介
上海新睿生物科技有限公司是一家专注于生命科学和生物技术领域的高科技企业，是国内代理销售生物试剂、仪器的知名公司之一。我们代理20多家欧洲，美国，日本等多家著名生物技术公司产品，销售的分子生物学、蛋白研究、免疫学、神经学、微生物培养、信号转导、细胞培养试剂和耗材等，已被广泛应用于生命科学基础研究、开发应用、制药、疾病诊断与控制、人口与健康、生物技术等诸多领域。客户遍布大学、研究所、医院、卫生防疫、商品检验检疫、制药公司、生物技术公司和食品工业等单位。我们竭诚为全国的顾客提供优质产品与服务。新睿公司的目标是在生命科学和生物技术领域内成为销售和研发生产为一体的一流企业。
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