细胞生物学试剂

ALK-1/ACVRL1 Fc Chimera Protein, Human

基本信息
产品名称:
ALK-1/ACVRL1 Fc Chimera Protein, Human
英文名称:
国产/进口:
国产
产地/品牌:
优爱(UA BIO)
型号:
500μg
参考报价:
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总点击数:
13
更新日期:
2026-01-30
产品类别:

性能参数

优爱(UA BIO),国产重组蛋白专家,
产品别名: ALK-1/ACVRL1 Fc Chimera Protein, Human

The Bone Morphogenetic Protein (BMP) receptor activin receptor–like kinase 1 (Alk1), which is predominantly expressed in the vascular endothelium, has been shown to play a critical role in angiogenesis. Embryos lacking Alk1 die early during embryonic development due to impaired vascular remodeling and lack of perivascular cell coverage. In renal physiology, Alk1 has been suggested to play an important role in the regulation of extracellular matrix deposition, including collagen type I and fibronectin, and Alk1 heterozygosity has been associated with increased renal fibrosis in a mouse model of obstructive nephropathy, probably due to the decrease in the Alk1/Smad1 antifibrotic/protective signaling in renal fibroblasts.

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优爱蛋白是优宁维集团旗下品牌,始终专注于为药物研发、细胞治疗、基因治疗及基础科研等领域提供全面的蛋白类试剂与技术服务。我们的产品涵盖药物靶点蛋白、细胞因子、工具酶、药物筛选与激酶检测试剂盒,同时承接蛋白定制表达、全长跨膜蛋白开发等高项目。

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