1. Published on 5 September, 2024 『Development』
Developing long bones respond to surrounding tissues by trans-pairing of periosteal osteoclasts and endocortical osteoblasts
Koichi Matsuo, Laboratory of Cell and Tissue Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.
2. Published on 27 December, 2024 『Cell Reports』Role of immature choroid plexus in the pathology of model mice and human iPSC-derived organoids with autism spectrum disorder
Toshifumi Fukuda, Laboratory of Regenerative Medicine, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan.
1. Published on 8 August 2024『Nature Cell Biology』Spindle architecture constrains karyotype evolutionLive-cell microscopy: SpinSR10(UPLSAPO100XS/UPLXAPO60XO)Jana Helsen, Gautam Dey, Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany.
Gavin Sherlock, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
2. Published on 30 September 2024『Nature Communications』CEP112 coordinates translational regulation of essential fertility genes during spermiogenesis through phase separation in humans and miceFRAP experiments: SpinSR10H&E staining: VS200Confocal microscopy: FV3000Xueguang Zhang, Xueguang Zhang, Gelin Huang, Ting Jiang, Tongtong Li, Wenming Xu, Joint Lab of Reproductive Medicine of SCU-CUHK, Lab of Reproductive genetics and Epigenetics, Department of Obstetrics/Gynecology, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, West China Second University Hospital, Sichuan University, China.
Lanlan Meng, Yueqiu Tan, Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive & Genetic Hospital of CITIC-Xiangya, China.
3. Published on 3 October 2024『Cell』TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survivalLive cell microscopy: SpinSR10(UPLSAPO60XS), cellSens Deconvolution
Pauline Lascaux, Kristijan Ramadan, The MRC Weatherall Institute of Molecular Medicine, Department of Oncology, John Radcliffe Hospital, University of Oxford, UK.
4. Published on 10 September 2024『Nature Genetics』Custom microfluidic chip design enables cost-effective three-dimensional spatiotemporal transcriptomics with a wide field of viewConfocal microscope: SpinSR10
Junjie Zhu, Kun Pang, Beiyu Hu, Fangqing Zhao, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
5. Published on 23 September 2024『Neuron』The sodium-bicarbonate cotransporter Slc4a5 mediates feedback at the first synapse of visionConfocal microscope: SpinSR10 (UPLSAPO40XS)
Rei Morikawa, Botond Roska, Institute of Molecular and Clinical Ophthalmology Basel, Switzerland.
6. Published on 27 September 2024『Cell』mTOR activity paces human blastocyst stage developmental progressionImmunofluorescence microscope: SpinSR10Dhanur P. Iyer, Aydan Bulut-Karslioğlu, Stem Cell Chromatin Group, Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Germany.
Heidar Heidari Khoei, Nicolas Rivron, Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Austria.
7. Published on 3 October 2024『Nature』Biomolecular condensates mediate bending and scission of endosome membranes | NatureConfocal microscopeYanning Wang, Shulin Li, Xiaofeng Fang, School of Life Sciences, Tsinghua University, China.Marcel Mokbel, Faculty of Mathematics and Informatics, Technical University Freiberg, Germany.
Roland L. Knorr, Institute of Biology, Faculty of Life Sciences, Humboldt-Universität zu Berlin, Germany.
8. Published on 11 October 2024『EMBO Molecular Medicine』Targeting USP11 regulation by a novel lithium-organic coordination compound improves neuropathologies and cognitive functions in Alzheimer transgenic miceConfocal microscope SpinSR10Yi Guo, Jun Tan, Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education; Key Laboratory of Molecular Biology Guizhou Medical University China.
Song Li, First Affiliated Hospital of Dalian Medical University China.
9. Published on 11 October 2024『Nature Communications』Four Core Genotypes mice harbour a 3.2MB X-Y translocation that perturbs Tlr7 dosageSpinning disc confocal microscope: IXplore SpinJasper Panten, Stefania Del Prete, James P. Cleland, Duncan T. Odom, Division of Regulatory Genomics and Cancer Evolution, German Cancer Research Center (DKFZ), Germany.
Edith Heard, European Molecular Biology Laboratory (EMBL), Germany.
10. Published on 21 October 2024『The EMBO Journal』Glutamine sensing licenses cholesterol synthesisSpinning disc confocal microscope: IXplore Spin
Bruna Martins Garcia, Lena Pernas, Max Planck Institute for Biology of Ageing Cologne Germany.
1. Published on 30 July, 2024 『Nature Communications』CRISPR-CasRx-mediated disruption of Aqp1/Adrb2/Rock1/Rock2 genes reduces intraocular pressure and retinal ganglion cell damage in mice
Jinhai Huang, Xingtao Zhou, Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; NHC Key laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China.
2. Published on 6 August, 2024 『Cell Metabolism』Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function
Ming Xu, UConn Center on Aging, UConn Health, Farmington, CT 06030, USA.
3. Published on 10 September, 2024 『Nature Communications』ARViS: a bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset cerebral cortex
Masanori Matsuzaki, Department of Physiology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.
4. Published on 19 September, 2024 『The Journal of Biological Chemistry』The N-acetylglucosaminyltransferase Radical fringe contributes to defects in JAG1-dependent turnover and signaling of NOTCH3 CADASIL mutants
Motoyuki Itoh, Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Chiba, Japan.
5. Published on 28 September, 2024 『Pediatric Research』Amyloid precursor protein as a fibrosis marker in infants with biliary atresia
Jan C. Kamp, Department of Respiratory and Infectious Medicine, Hannover Medical School, Hannover, Germany.
6. Published on 13 November, 2024 『Nature Aging』Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing
Ming Xu, UConn Center on Aging, UConn Health, Farmington, CT, USA.
7. Published on 20 November, 2024 『eLife』Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway
Toshimasa Yamauchi, Masaki Igarashi, Department of Diabetes & Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
8. Published on 2 December, 2024 『Scientific Reports』Development of a novel gut microphysiological system that facilitates assessment of drug absorption kinetics in gut
Yuzuru Ito, Institute of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8572, Ibaraki, Japan.
9. Published on 2 December, 2024 『The Journal of Neuroscience』Striosome circuitry stimulation inhibits striatal dopamine release and locomotionHaruhisa Inoue, Institute for Advancement of Clinical and Translational Science (iACT), Kyoto University Hospital, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Ryosuke Takahashi, Department of Neurology, Graduate School of Medicine Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
1. Published on 1 January, 2025 『Nature』FBP1 controls liver cancer evolution from senescent MASH hepatocytes
Li Gu, Yahui Zhu, Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.
2. Published on 2 January, 2025 『Nature Cardiovascular Research』Mechanical regulation of macrophage metabolism by allograft inflammatory factor 1 leads to adverse remodeling after cardiac injuryEdward B. Thorp, Department of Pathology, Northwestern University, Chicago, IL, USA.
Matthew DeBerge, Department of Anesthesiology, Critical Care, and Pain Medicine, The University of Texas Health Science Center, Houston, TX, USA.
3. Published on 2 January, 2025 『Cancer Research』Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
Priyamvada Rai, Division of Biology, Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida.
4. Published on 2 January, 2025 『Nature Cardiovascular Research』Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration
Jeroen Bakkers, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, Utrecht, The Netherlands.
5. Published on 3 January, 2025 『Nature Communications』Allocentric and egocentric spatial representations coexist in rodent medial entorhinal cortex
Sheng-Jia Zhang, Department of Neurosurgery, Xinqiao Hospital, Army Medical University, Chongqing, China.
6. Published on 8 January, 2025 『The Journal of Experimental Medicine』Differential impact of lymphatic outflow pathways on cerebrospinal fluid homeostasis | Journal of Experimental Medicine
Jonathan Kipnis, Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA.
7. Published on 9 January, 2025 『Cell Reports』Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation
Wei Hua, Ying Mao, Dan Ye, Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
1. Published on 14 February, 2024 『Science Translational Medicine』Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapyWei Zuo, Department of Organ Regeneration, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.Shiyue Li, Nanshan Zhong, State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease,Guangzhou Medical University, Guangzhou 510120, China.
Xiaotian Dai, Southwest Hospital, Third Military Medical University of PLA, Chongqing 400038, China.
2. Published on 29 May, 2024 『Scientific Reports』A novel strategy to facilitate uniform epithelial cell maturation using liquid–liquid interfaces
Rie Sonoi, Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-Ku, Fukuoka, 819-0395, Japan.
3. Published on 27 June, 2024 『Scientific Reports』Detrimental interactions of hypoxia and complement MASP-1 in endothelial cells as a model for atherosclerosis-related diseases
László Cervenak, Research Laboratory, Department of Internal Medicine and Haematology, Semmelweis University, Szentkirályi U. 46, Budapest, 1088, Hungary.
4. Published on 21 August, 2024 『Langmuir』Cell Cycle Modulation through Physical Confinement in Micrometer-Thick Hydrogel Sheaths
Shinji Sakai, Division of Chemical Engineering, Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan.