在落幕的 ACS Spring 2025 (美国化学会春季年会) 上，多个创新药物首次披露，涵盖了肿瘤、心血管、神经系统疾病等多个领域。

这些小分子药物代表了当下最前沿的药物化学设计趋势。这些首次亮相的“新星”是否有望成为下一代重磅新药？跟随小 M 一起来看看它们的背景信息。

 
Section
小结

这 12 个首次亮相的小分子药物，不仅展示了目前药物研发的多样化方向 (从传统抑制剂到蛋白降解剂、共价靶向剂、大环肽等)，也反映出精准医疗背景下对突变蛋白、肿瘤微环境、脑部靶点等复杂机制的深入探索。部分分子已经进入临床阶段，值得持续关注。
 

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